Smoking Cessation

Question 1

Nicotine

Answer 1

Effects CNS, CV, and GI stimulation

Crosses blood-borne barrier instantly

Question 2

Nicotine Replacement Therapy

Answer 2

-Transdermal patches, gum, lozenges
(Nicoderm, nicorette, nicotrol, commit lozenge)

DO NOT USE if continue to smoke- high levels of nicotine can be toxic

Question 3

Smoking Cessation Medications

Answer 3

1. bupropion (wellbutrin, zyban)
   -wellbutrin is antidepressant, zyban for smoking (difference in dosage)
2. Varenicline (Chantix) - competes with nicotine receptors
   Dosing- start with 0.5 mg daily for days 1-3, then 0.5 mg bid days 4-7; Stop smoking on day 8 then 1 mg bid for at least 12 wks.
   ADR- mood and behavior changes, INSOMNIA

pilots, bus drivers, etc. CAN NOT TAKE PER National Transportation of Safety