Smallies 9 Flashcards
What is the evaluation of clear fluid from a diagnostic peritoneal lavage?
No obvious injury/peritoneal disease
What is the evaluation of opaque and bloody fluid from a diagnostic peritoneal lavage?
Haemorrhage
What is the evaluation of fluid that gets darker with each attempt when performing a diagnostic peritoneal lavage?
Continued haemorrhage
What is the evaluation of turbid/cloudy fluid from a diagnostic peritoneal lavage?
Peritonitis
What is the evaluation of bluish/greenish fluid from a diagnostic peritoneal lavage?
Bile leakage or upper GI leak
What is the evaluation of finding fluid with a PCV of <2% from a diagnostic peritoneal lavage?
mild haemorrhage
What is the evaluation of finding fluid with a PCV of 3-10% from a diagnostic peritoneal lavage?
moderate haemorrhage
What is the evaluation of finding fluid with a PCV of >10% from a diagnostic peritoneal lavage?
severe haemorrhage
What is the evaluation of finding fluid with white cells >1000x10^9 from a diagnostic peritoneal lavage?
mild peritoneal irritation
What is the evaluation of finding fluid with white cells >2000x10^9 from a diagnostic peritoneal lavage?
marked peritoneal irritation
What is the evaluation of finding fluid with more amylase than serum from a diagnostic peritoneal lavage?
Pancreatitis, trauma, small bowel leak
What is the evaluation of finding fluid with more ALK phosphatase than serum from a diagnostic peritoneal lavage?
Trauma, ischaemia, leakage
What is the evaluation of finding bilirubin in the fluid from a diagnostic peritoneal lavage?
Leak from biliary tract/bowel
What is the evaluation of finding fluid with more creatinine than serum from a diagnostic peritoneal lavage?
Uroabdomen
What is the evaluation of finding fluid with neutrophilia (toxic neutrophils) from a diagnostic peritoneal lavage?
suppurative peritonitis
What is the evaluation of finding fluid with plant material from a diagnostic peritoneal lavage?
GI leak
What is the evaluation of finding neoplastic cells in the fluid from a diagnostic peritoneal lavage?
neoplasia
What is the evaluation of finding fluid with more triglycerides than serum from a diagnostic peritoneal lavage?
chyloabdomen
What is GVD?
Gastric dilatation volvulus, also known as gastric dilation, twisted stomach, or gastric torsion, is a medical condition that affects dogs in which the stomach becomes overstretched and rotated by excessive gas content
What are the mortality rates with surgery for a GDV patient?
10-18%
List extrinsic risk factors of GDV
Diet Post prandial exercise Pre-prandial exercise Single daily feeding Hospitalisation – increased stress
List intrinsic factors of GDV
Breed (deep-chested) Body size Thoracoabdominal dimensions Gastric volume Gastric position Gastric ligament laxity (hepatoduodenal and hepatogastric) Eructation control Pyloric canal function A parent (1st degree relative) who has experienced a GDV – don’t breed from dogs who have had a GDV Temperament and “happiness”
List breeds predisposed to GDV
Great Dane, St Bernard, Weimaraner, Irish Setter, Gordon Setter, Standard Poodle, Basset Hound, Doberman Pinscher, Old English Sheepdog, German Shorthaired Pointer
What is the aetiology of GDV?
Multifactorial Aerophagia leading to gastric dilation Abnormal oesophageal motility Dysphagia Gas or fluid accumulate in stomach and the normal means of relief (vomiting, regurgitation, pyloric function) have become inoperative
Is clockwise or anti-clockwise rotation more common with GDV cases? And what is the maximum rotation for each way?
Clockwise; most common, max rotation of 270-360 degrees
Anti-clockwise; rare, max rotation of 90 degrees
Describe the roation in GDV
Generally (in GDV) the stomach rotates in a clockwise manner when viewed from the surgeon’s perspective (dog on its back, clinician at dog’s side facing cranially (rotation can be 90-360 degrees).
Gastric dilatation usually precedes volvulus; twisting occurs passively due to the alteration of anatomical relationships by the progressively ballooning stomach. As the stomach dilates, it pushes dorsal and the pylorus becomes ventralised. Once it has twisted it is not likely to untwist. When the stomach twists, it rotates into the omental bursa.
What will you typically see when you open up a dog with GDV?
You will see a single layer of omentum overlying the stomach when you open the dog up
What are the resultant pathophysiological events of a GDV?
Hypovolaemia Endotoxaemia Hypoxia Cardiac dysfunction Gastric ischaemia and mucosal necrosis Splenic ischaemia/infarction
What is the pathophysiology of local events at the stomach with a GDV case?
Gastric wall blood supply disrupted – avascular necrosis and infarction most likely on the greater curvature of the stomach (Leads to rupture and peritonitis)
As the greater curvature of the stomach is displaced the gastric branches of the splenic artery can avulse
Haemorrhage and ischaemia result
Perfusion pressure falls
Mechanical obstruction to vessels (caudal vena cava and portal vein)
Thrombi (due to clotting) can develop if the blood flow slows down
Gastric necrosis (most commonly greater curvature)
What is the pathophysiology of local events at the spleen with a GDV case?
Displaced as greater curvature of the stomach moves
Venous congestion due to compromised venous drainage
Splenic artery avulsions can occur
Infarction (arterial supply decreased due to congestion downstream)
Splenic torsion
Splenomegaly due to congestion can occur
What are the pathophysiological systemic consequences in a GDV case?
Blood flow obstruction e.g. caudal vena cava and hepatic portal vein
Venous return decreased and cardiac output falls
Heart rate increases
o Myocardial oxygen demand increases
o Myocardial oxygen delivery is falling
Poor perfusion and stasis
Arrhythmias
Ischaemic reperfusion injury (IRI)
Gastric perforation – adversely affects prognosis (PTS/death likely)
Septic peritonitis
Post-operative disseminatied intravascular coagulation (DIC)
Post-operative Systemic Inflammatory Response Syndrome (SIRS)
What are the presenting signs of a GDV case?
Progressively expanding and tympanic abdomen – care with giant breeds, the ribs cover the stomach
Dog depressed, may be recumbent
In ‘shock’, CRT prolonged, pale
Tachycardia, poor pulses, tachypnoea
Dog exhibiting signs of pain
May shown signs of non-productive retching/vomiting (if they can produce vomit this does not mean they don’t have a torsion)
Restless
What should be included in the diagnostic work up of a GDV case?
Clinical signs Assess severity of shock Electrolytes Acid/base status Electrocardiogram Radiography
What are the therapeutic goals of GDV?
Restore and support the circulation
Provide oxygen to help the oxygen demand on the heart and to the periphery
Decompress the stomach
Work out if it is GD or GDV? Not always clear cut, even with radiography
Surgical planning to untwist the stomach
Prophylactic gastropexy – prevent it happening again (may not be performed at the same time as the fixative surgery)
What does the initial management of GDV consist of?
First priority is to treat shock Fluid therapy Decompression ECG – treat dysrhythmia? IV corticosteroids – may or may not be beneficial but won’t do any harm as a single injection
What do we what to measure in the blood of a GDV patient?
PCV and TS
Electrolytes
Lactate
Venous blood gases
What are we looking for in the venous blood gases of a GDV patient?
Metabolic acidosis, tissue hypoperfusion, anaerobic metabolism and lactate accumulation
What type of fluids are suitable for a GDV case?
A balanced eletrolyte solution e.g. Hartmanns (first choice) or 0.9% NaCl
What rate should we give crystalloids to a GDV patient?
Shock dose (90ml/kg) give a proportion
E.g. 20-25ml/kg over first 10-15 mins
Repeat as necessary (up to 90ml/kg
What can you use as a last resort in a GDV case (aka the dog is dying in front of your eyes)?
Give hypertonic saline (7.2%) (1ml/kg/min)