Small Molecule Drugs Flashcards
1
Q
Breast
A
Tamoxifen aromatise inh
Targets Oestrogen receptor, blocks ER
2
Q
Melanoma
A
Vemurafenib
Inh BRAF V600E protein, triggers apoptosis
3
Q
NSCLC
A
Crizotinib, Brigatinib, Lorlatinib
Targets EML4ALK fusion protein
Inh abnormal signaling
osimertinib, afatinib
targets EGFR mutation, blocks signaling
4
Q
Checkpoint inh
A
For bladder, cervical, colorectal, kidney, 3- breast
