Monoclonal Antibodies Flashcards
1
Q
Breast
A
Trastuzumab, pertuzumab
Targets HER2 receptor
Blocks downstream signalling
2
Q
Colon
A
Cetuximab, panitumimab
Binds to EGFR and blocks signalling
3
Q
PD1 on T cells
A
Pembrolizumab, nivolumab
Binds to PD1, stops it from binding to PDL1, boosting immune response
4
Q
PDL1 on cancer cells
A
Atezolizumab, avelumab, durvalumab
Binds to PDL1, stops it from binding to PD1, boosting immune response