Monoclonal Antibodies Flashcards

1
Q

Breast

A

Trastuzumab, pertuzumab
Targets HER2 receptor
Blocks downstream signalling

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2
Q

Colon

A

Cetuximab, panitumimab
Binds to EGFR and blocks signalling

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3
Q

PD1 on T cells

A

Pembrolizumab, nivolumab
Binds to PD1, stops it from binding to PDL1, boosting immune response

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4
Q

PDL1 on cancer cells

A

Atezolizumab, avelumab, durvalumab
Binds to PDL1, stops it from binding to PD1, boosting immune response

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