Slides Flashcards
When is the characteristic shape of the stomach seen in embryo development?
7th week
Whats the diaphragm formed from?
Septum transversum in embryo
When the spleen formed? What from?
Aggregation of mesenchymal cells in 5th week
Describe pancreas development
Ventral bud closely associated with gall bladder and bile duct
Dorsal bud from duodenum tube
When duodenum rotates buds come into contact
Occurs in weeks 5-8
What part of the pancreas is formed from the ventral bud?
Uncinate process
What forms from the ventral mesogastrium?
Falciform ligament and lesser omentum
What forms from the dorsal mesogastrium?
Greater omentum
gastrosplenic ligament
splenorenal ligament
Describe the lesser omentum
Connects liver to lesser curvature of stomach
Has a free edge so folds back to create a double layer containing hepatic artery, the common bile duct, the portal vein, lymphatics, and the hepatic plexus of nerves
What is the vitelline duct?
Elongation of gut tube in 5th week causes it to bulge ventrally as the vitelline duct
What happens in the 6th-9th week of development for the gut tube?
Loop of GI tract enters umbilical coelom and begins anticlockwise rotation (so that SMA is anterior to duodenum)
Vitelline duct then regresses and proximal limb elongates and becomes pleated
What happens in week 10 of development of the gut tube?
Rotation continues
Gut tube renters abdomen, proximal limb first
Distal limb elongates and rotates so caecum is in R iliac fossa and the greater omentum then grows
Whats an omphalocele?
When gut fails to re-enter abdomen at week 10, leading to amnion covered intestines outside of anterior abdominal wall
What abnormalities can occur if the vitelline duct doesn’t regress properly?
Meckel’s diverticulum, Umbilicoileal fistula, volvulus
What can occur if the gut doesn’t rotate properly?
Nonrotation-> odd placement
Volvulus->obstructed duodenum
Reverse rotation-> duodenum anterior to colon-> SMA can compress colon
Partial rotation-> subhepatic caecum
What happens between weeks 4-7 in the hindgut?
Urorectal septum elongates so cloacal membrane now urogenital membrane+ anal membrane
Mesenchyme then proliferates-> anal pit