Slide 5 Flashcards
What are two types of cytokines that control inflammation?
Pro-inflammatory & anti-inflammatory cytokines
What is the main purpose or for pro-inflammtory cytokines?
To promote inflammation and help fight infection or injury
Which immune cells release TNF-a?
Mast Cells
What does TNF-a do in the inflammatory response?
It activites other immune cells and amplifies inflammation
What does IL-1 act as in the immune system?
A growth factor to stimulate immune cell activity
Which cells produce IL-1?
Macrophages
What is the role of IL-6 in the immune system? It signals what type of cell?
It signals liver cells to produce immune-related proteins and stimulates blood cell growth
What is the job of anti-inflammatory cytokines?
to reduce inflammation and prevent tissue damage
What does TNF- B help regulate?
Immune cell activity and inflammation reduction
Which cytokine helps prevent excessive immune activation?
IL-10
Why is it important to balance inflammation?
Too much can cause tissue damage, and too little can allow infection to spread
What happens if inflammation isn’t turned off?
Cell damage
Which cytokines help turn off inflammation once the threat is under control?
IL-10 & TNF-B
What type of cytokines help amplify the inflammatory response?
Pro-inflammatory cytokines
How do anti-inflammatory cytokines protect the body?
They prevent excessive immune responses from damaging healthy tissues
