Sleep Disorders

Question 1

Classifications of Narcolepsy

Answer 1

Narcolepsy type 1 (WITH cataplexy)
Narcolepsy type 2 (WITHOUT cataplexy)

Question 2

What hormone is deficient in T1 Narcolepsy?

Answer 2

Orexin

Question 3

Proportion of NREM and REM sleep

Answer 3

NREM - 80%
REM - 20%

Question 4

OSA Definition / Polysomnography findings

Answer 4

Upper airway narrowing/closure w/ ongoing respiratory effort

On polysomnography -> apnoea followed by respiratory effort

Question 5

CSA Definition / Polysomnography findings

Answer 5

Reduction/cessation of airflow due to absent/reduced respiratory effort

On polysomnography -> Apnoea not followed by respiratory effort

Question 6

CSA Mx

Answer 6

Treat underlying pathology - optimise HF therapy

1st line therapy - CPAP, O2 if hypoxaemic while sleeping
2nd line therapy - Adaptive seroventilation (contraindicated if EF <40%)

Question 7

Narcolepsy Mx

Answer 7

Stimulant therapy - dexamphetamine
SSRI/SNRI for cataplexy

Question 8

CSF findings in T1 Narcolepsy

Answer 8

Low hypocretin levels

Question 9

Insomnia Mx

Answer 9

CBT