Sleep Disorders Flashcards
Drugs used for Restless Leg Syndrome
Gabapentin
Pramiprexole (Mirapex)
Ropinirole (Requip)
Rotigotine (Neupro) patch - daily
Drug class used in Narcolepsy
Stimulants (modafinil, armodafinil, methylphenidate, etc)
What drug class requires a 14-day washout period in someone who has been using phenelzine?
TCAs (Doxepin)
*Phenelzine is a MAOI
Date rape drug
Sodium oxybate
- if used as C-I (illicit drug)
- C-III used for Narcolepsy
- REMS program
Counseling pearl for pramiprexole and ropinirole
Take 1-3 hours before bedtime
Drug class of choice used for RLS
Dopamine agonists
*also used in Parkinson’s
What drugs increase GABA leading to an inhibitory effect by binding to benzodiazepine receptor-subtypes specific for sedation?
Eszopiclone
Zolpidem
Zaleplon
Zolpidem formulations
Oral spray & IR, CR, and SL tablet
Medical Terminology for unusual actions while sleeping, of which the patient may not be aware of is called?
Associated with what drugs?
Parasomnias
Drugs: Eszopiclone, Zaleplon, & Zolpidem
Beers Criteria drug classes
Benzodiazepines (triazolam)
Non-benzos (zolpidem)
1st- gen antihistamines (benadry)
Need Help Falling Asleep?
Eszopiclone
Zaleplon
Zolpidem
Ramelteon
Need Help Staying Asleep?
Eszopiclone
Zolpidem
Suvorexant
Doxepin
Need Help Falling & Staying Asleep?
Eszopiclone
Zolpidem
Name the hypnotics & antidepressants drugs.
“CIV”
Zolpidem (Ambien)
Zaleplon (Sonata)
Eszopiclone (Lunesta)
Suvorexant (Belsomra) - orexin-receptor antag
Ramelteon (Rozerem) - melatonin-receptor agonist
Doxepin ER (Silenor) - antidepressant
Diagnosis for Insomnia
Having symptoms at least 3x/week for > 3 months
Sx: falling asleep, staying asleep, awakening after sleep onset
Drugs that can worsen insomnia
Alcohol Stimulants Bupropion Caffeine PSE Diuretics Fluoxetine Steroids Varencline
Natural Products for Sleep
Chamomile Tea
Valerian
Melatonin
Drug used for non-24 hour sleep-wake disorder
tasimelteon (Hetlioz)
Horizant generic
gabapentin enacarbil
