Sleep Disordered Breathing Flashcards

1
Q

Apnea is defined as

A

Decrease in thermal sensor amplitude by > 90% for > 10 seconds

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2
Q

Define which patients need OSA treatment

A

1) Mild OSA who are symptomatic or have comorbidities

2) Mod to severe OSA regardless of symptoms or comorbid conditions

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3
Q

Define CPAP compliance

A

> 4 hours use on at least 70% observed nights

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4
Q

Best historic predictor of OSA

A

Witnessed apneas

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5
Q

In-lab PSG needed for patients with the following conditions (list 4)

A

Stroke
CV Disease
COPD
Hypoventilation syndromes

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6
Q

Goal of CPAP therapy

A

1) attempt AHI < 5

2) At least 50% reduction in original AHI

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7
Q

Which patents are candidates for oral devices

A

Snoring and mild-mod OSA intolerant of CPAP

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8
Q

Which surgery is successful in resolving OSA

A

Maxillomandibular advancement

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9
Q

Define pathophysiology of Cheynes-Stokes Respirations

A

1) increased chemoreceptor sensitivity to CO2
2) increased ventilatory drive
3) Increased circulation time d/t low CO
4) decreased O2 reserve

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10
Q

What stages of sleep does nonhypercapnic central sleep apnea typically occur in?

A

N1 and N2

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11
Q

Treatments for Cheynes-Stoke Respirations (list 2)

A

1) Treat underlying heart failure

2) Adaptive servo-ventilation

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12
Q

Complex sleep apnea is defined as

A

Emergence of CSA with treatment of OSA

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13
Q

Treatment of complex sleep apnea includes

A

1) Continued CPAP treatment of OSA

2) Reducing PAP may resolve complex events

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14
Q

High altitude periodic breathing is treated with

A

1) oxygen

2) Diamox

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15
Q

Hypercapnic central sleep apnea is usually a result of which drug class

A

Opiates

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16
Q

Differentiate between Cheynes-Stoke and Biot respirations

A

Biot shows irregular periods of apnea contrasting with regular periods of apnea in CSR

17
Q

Mixed apneas are

A

Central sleep apnea followed by obstructive sleep apnea

18
Q

OHS is diagnosed by two things

A

Awake PCO2 > 45

BMI > 30

19
Q

Congenital Central Hypoventilation is related to mutations in which gene

A

PHOX2B