Sleep Disorder: Insomnia, Restless Legs Syndrome (RLS) & Narcolepsy Flashcards
How is chronic insomnia diagnosis?
Patient must have insomnia for at least 3 times per week for at least 3 months
What are some natural products used in the treatment of Insomnia?
Melatonin (3 - 5 mg QHS)
Valerian
Chamomile tea
What are some drugs which can worsen Insomnia?
Alcohol Bupropion Caffeine Decongestants (e.g. pseudoephedrine) Fluoxetine if taking in the evening Steroids Stimulants Verenicline (Chantix)
What is the first-line therapy for Insomnia?
Sleep hygiene
What is the drug recommendation with patients needing help falling asleep?
Eszopicolon (Lunesta)
Zolpidem (Ambien)
Ramelteone (Rozerem)
Zaleplon (Sonata)
What is the drug recommendation with patients needing help staying asleep?
Eszopicolon (Lunesta)
Zolpidem (Ambien)
Doxepin
Suvorexant
What is the drug recommendation with patients needing help both falling and staying asleep?
Eszopicolon (Lunesta)
Zolpidem (Ambien)
What are some first generation antihistamine OTC drugs patient can self treat Insomnia with?
Diphenhydramine (Benadryl)
Doxylamine (Unisom)
What drugs are Not recommended for Chronic Insomnia?
Diphenhydramine Melatonin Trazodone Valarian Tiagabine
True or False: Lunesta is preferred over Benzodiazepines in the treatment of Insomnia.
True
What schedule are Ambien, Lunesta and Sonata?
IV
What are 3 off-lable drugs used for Insomnia treatment?
Doxepin (Silenor)
Mirtazapine (Remrone)
Trazodone (Desyrel)
Which Benzodiazepines are used in the treatment of Insomnia?
Lorazepam (Ativan)
Temazepam (Restoril)
note: these 2 are also in the LOT group of benzodiazepines so are safest of the benzodiazepines to be used in the elderly or in patients with liver impairments
What 2 drug classes are used in the treatment of Restless Leg Syndrome?
Dopamine agonists
and
Anticonvulsants (Gabapentin)
Dopamine agonist agents used in the treatment of Restless Leg Syndrome
Pramipexole (Mirapex)
Ropinirole (Requip)
Rotigotine (Neupro) patch formulation
