Attention Deficit Hyperactivity Disorder (ADHD) Flashcards
What are the primary symptoms of ADHD?
Inattention
Hyperactivity
Impulsivity
ADHA pathophysiology
Defects in the Dopamine pathway that regulate reward anticipation and emotional self-regulation may play a role
ADHD drug, aka Stimulants, MOA
Rise Dopamine and Norepinephrine levels
What is the first-line treatment in ADHD?
Cognitive behavioral therapy
What is an example of a non-stimulant medication used in ADHD?
Strattera (Atomoxetine)
Second line therapy but can be used as first line if there is concerns of drug abuse
What is the first-line drug class in ADHD?
Stimulants (taken in the am)
Non-stimulants can be used as first line if there is concerns of drug abuse
Stimulants agents
Methylphenidate ER (Concerta) Methylphenidate patch (Daytrana) Methylphenidate IR (Ritalin) Dexmethylphenidate (Focalin) Lisdexmethylphenidate (Vyvanse) Adderall XR and IR
What are some add-on medications in the treatment of ADHD?
Intuniv (Guanfacine)
Kapvay (Clonidine) (QHS)
Both Alph-2a Adrenergic Receptor Agonists
Do stimulant drugs need to be tapered off when discontinuing?
Nope
Stimulant BBW
High potential for abuse and dependence
Stimulant and non-stimulants contraindications
Cannot be taken within 14 days of an MAOI
Which stimulant has the least potential for abuse?
Lisdexamfetamine (Vyvanse)
Can Strattera capsules be opened?
Nope
Does Intuniv (Guanfacine) need to be tapered off when discontinuing? Why or why not?
Yes
b/c it may cause rebound hypertension
What is the starting dose for Methylphenidate IR (Ritalin)?
5 mg BID before breakfast and lunch
