Sleep 2 Flashcards
1
Q
AAS 1st pathway
A
Brainstem: Dorsal Raphe and LC
Posterior hypothalamus: Tubermammilary nucleus, Vebtnral PAG
Basal forbrain
2
Q
AAS 2nd Pathway
A
Cholintergic in Pedunculopontine nucleus (PPT) Laterodorsal tegmental nucleus (LDT)
3
Q
Where is the main sleep centre
A
Venterolateral preoptic nuclueus
4
Q
Proof of VLPO
A
Von economo showing anterior hypothalamus lesion causes insomnia
Lu et al 2000 show that if you ablate VLPO, you get a lot less sleep
Kroeger et al 2018 showed that activating VPLO and GAL neurons increased sleep
5
Q
REM ON nurons
A
Sublaterodorsal nucleus (SLD) Precoruleus region (PC)
6
Q
REM OFF neurons
A
Lateral pontine tegmentum (LPT)
Venterolateral PAG
