Sleep Flashcards

1
Q

Definitions of apnea adult vs pediatric

A

Adult: Apnea is defined by cessation of air movement for at least 10 seconds.
Pediatric: Cessation of air movement over two breath cycles.

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2
Q

Definitions of hypoventilation

A

Sleep related hypoventilation is defined as >10 mmHg increase in pCO2 compared to awake for at least 10 minutes OR rise in pCO2 > 55 mmHg for at least 10 minutes.

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3
Q

Definition of hypopnea

A

Decrease of air movement >/_ 30% for OVER 10 seconds, WITH at least 3% decrease in O2 sats (4% for medicare) (over 10 seconds for adults, over 2 breaths for kids)

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4
Q

Definition of arousal

A

Defined by an abrupt shift of EEG >16 Hz lasting at least 3 seconds.

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5
Q

What is the Mueller maneuver?

A

Performed with patient awake sitting up or supine. Patient asked to perform a valsalva while scope assess the degree of retropalatal or retrolingual collapse.

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6
Q

Sleep terror vs nightmare?

A

Sleep terrors - Occur in 1st third of night, non REM. Usually in kids, wake up scared, confused (don’t necessarily remember).
Nightmare - Occur during REM sleep. Patient wake up and can remember their dream (not confused).

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7
Q

What test to use for narcolepsy and results interpretation? ALSO type I vs type II narcolepsy?

A

MSLT < 8 minutes and rapid onset of REM (during PSG) are characteristic for narcolepsy.
Increased stage I sleep
Type I: WITH cataplexy, LOW CSF hypocretin
Type 2: WITHOUT cataplexy, NORMAL CSF hypocretin –> MOST COMMON TYPE!

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8
Q

What is periodic limb disorder?

A

Periodic limb disorder refers specifically to repetitive movement of anterior tibialis muscle.

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9
Q

What is RDI?

A

Respiratory disturbance index: apnea + hypopnea plus RERAs divided by total sleep time

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10
Q

What is OSAHS score?

A

Calculated by adding grades for BMI, tonsil size and Friedman tongue size. Scores of 8 or more have 90% chance of having at least moderate OSA.

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11
Q

Findings for Awake, REM, N1, N2, N3, and OSA on sleep study?

A

Awake - beta waves (beta off awake)!
Relaxed wakefulness - Alpha waves
REM - Sawtooth, rapid eye movements, 25% of sleep
N1 - Vertex sharp waves
N2 - K complexes and sleep spindles,** 50% of night**, 2nd half of night
N3 - Delta (Deepest sleep, 1st half of night)
OSA - Irregularity/flattening on PTAF and airflow tracings

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12
Q

Current criteria for INSPIRE?

A

Age >18
AHI 15 to 65, non-obstructive events <25% of total events, BMI<35 (although many commercial insurers use BMI<32), CPAP intolerance
Absence of complete concentric collapse at the velum on DISE.

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13
Q

What is periodic limb movement disorder defined as (PLMI) and first line treatment?

A

PLMI > 5/h and TX: Iron, dopamine agonists (pramipexole)

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14
Q

Definition of Apnea Index? Apnea Hypopnea Index?

A

Apnea Index: Apnea/Hr
Apnea Hypopnea Index: Apnea + Hypopnea/Hr

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15
Q

Indications for PSG in a pediatric patient?

A

-Confirm OSA prior to T&A
-POST OP PSG indicated in those who had preoperative evidence of moderate to severe OSA; obesity; craniofacial anomalies obstructing the upper airway; or neurologic disorders, such as Down syndrome, Prader-Willi syndrome, and myelomeningocele.
-PSG should be considered in children with chronic asthma, cystic fibrosis, pulmonary hypertension, bronchopulmonary dysplasia, or chest wall abnormality if there is clinical suspicion of an accompanying sleep-related breathing disorder.
***

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16
Q

What muscles do you include and exclude in INSPIRE?

A

Include the genio muscles and C1 (branch to geniohyoid)
Exclude styloglossus and hyoglossues (they retract the tongue)

17
Q

Periodic Limb Movement Disorder Criteria for adults vs children?

A

Adults: 15 or greater movements/hour
Kids: 5 or greater movements/hour

18
Q

What does expansion pharyngoplasty entail?

A

Tonsillectomy/UPPP + rotation of the palatopharyngeal muscle (tunnel reaches hamulus of medial pterygoid).

Of note - a LATERAL pharyngoplasty involves the superior constrictor muscles instead.

19
Q

VOTE Scoring for DISE

A

Velum, Oropharynx, Tongue base, Epiglottis
0 - No collapse
1- Partial collapse
2- Complete collapse
(Specify AP, lateral or concentric collapse)

20
Q

What is the STOP BANG score?

A

Snoring, Tiredeness, observed apneas, increased blood pressure
BMI > 35, Age > 50, neck circumferance > 40 cm, male gender
One point for each, score of 3 or higher = high risk for OSA.

21
Q

What is upper airway resistance syndrome?

A

15 or more RERAs per hour
(Seen in younger non obese females)

22
Q

When is in lab PSG (type I) indicated over home sleep study?

A

In patient with: significant cardiorespiratory disease, potential respiratory muscle weakness due to neuromuscular conditions, awake hypoventilation or suspicion of sleep-related hypoventilation, chronic opioid medication use, history of stroke, or severe insomnia.

23
Q

Types I-4 sleep study features and most common?

A

Type I: In lab
Type II: HOME with at least 7 channels including EEG
Type III: HOME with at least 4 channels (MOST COMMON)
Type IV: HOME with at least 3 channels, not used often

24
Q

Treatment for narcolepsy?

A

Stimulants such as modafinil. TCAs + SSRI can also help with cataplexy.
Gamma hydroxybutuerate also approved for narcolepsy with cataplexy

25
Q

1st stage of stanford protocol and 2nd stage?

A

1st: UPPP, genioglossus advancement, hyoid suspension
2nd: Maxillomandibular advancement
*UPPP + tongue suspension = better results than UPPP alone
*Maxillomandibular advancement = comparable effects on AHI as CPAP

26
Q

What facial features increase risk of OSA?

A

Decreased maxillary and mandibular projection, low hyoid, INCREASED vertical facial length, increased tongue size, increased length + width of soft palate

27
Q

What sleep stages are increased with OSA?
What sleep stages decrease with age?

A

OSA: INCREASED Stage 1 and 2, DECREASED Stage 3 + REM
Aging: Decreased Stage 3