Histopathology

Question 1

What IAC tumor is this and describe the histopath features?

Answer 1

Densely packed scwhanomma cells (Antoni A areas) within loosely packed cells (Antoni B cells). Verocay bodies (pink) surrounded by nuclear palisading.
Vestibular schwanommas = 90% of all CPA tumors.

Question 1

What salivary gland tumor is this?

Answer 1

Warthin’s tumor (papillary proliferation lined with bi-layer epithelium).
-Motor oil fluid within cyst is pathognomic for Warthin’s!

Question 2

What are physalisiferous cells associated with?

Answer 2

Chordoma (abundant vacuolated cytoplasms)

Question 3

What salivary gland tumor is this?

Answer 3

Adenoid cystic - swiss cheese!
Three types: Tubular, Cribiform with < 30% solid, Cribiform > 30% solid (worse prognosis)

Question 4

What thyroid cancer is associated with “plasmacytoid morphology” and what is recommended TX?

Answer 4

Medullary thyroid carcinoma, needs total thyroidectomy central ND (+ lateral ND if obvious nodes on imaging)

Question 5

What tumor is this associated with and what is the main feeding artery?

Answer 5

Zelballen, associated with glomus tumors, ascending pharyngeal artery, SDH mutation
-Salt and pepper appearance on MRI
-Test to make sure its not secreting catecholamines (remove if so)

Question 6

What salivary tumor is this?

Answer 6

-Low grade mucoepidermoid (lots of mucous), high grade = more squamous components
-Most common salivary gland malignancy

Question 7

What IAC tumor does this describe:
Spindle cells arranged in nest and psamomma bodies

Answer 7

Meningioma!

Question 8

What nasopharyngeal mass might you suspect this is?

Answer 8

JNA
The pathology shows Intricate mixture of stellate and staghorn blood vessels with variable vessel wall thickness.