Skin Path - Terms

Question 1

Single layer of dividing cells that give rise to all epithelial cells

Answer 1

Stratum germinative (basal layer)

Question 2

Layer of keratinocytes that mature and acquire keratin as they are pushed toward the surface; thickest

Answer 2

Stratum spinosum (squamous layer)

Question 3

Thin layer that acquires large basophilic granules called keratohyalin

Answer 3

Stratum granulosum (granular layer)

Question 4

Composed of orthokeratin (without nuclei)

Answer 4

Stratum corneum

Question 5

Epithelial projections that anchor epithelium to underlying CT (dermis)

Answer 5

Rete ridges

Question 6

Reticulin fibers that act as a scaffold for epidermis

Answer 6

Basement membrane

Question 7

Loose collagen and elastin directly below and on the side of rete ridges.

Answer 7

Papillary dermis

Question 8

Dense structural collagen

Answer 8

Reticular dermis

Question 9

Clear cells living in the basal layer

Answer 9

Epidermal melanocytes

Question 10

Spindly cells living in papillary dermis

Answer 10

Dermal melanocytes

Question 11

Dendritic histolytic antigen processing cells living in stratum spinosum

Answer 11

Langerhans cells

Question 12

Live in the basal layer

Answer 12

Merkel cells

Question 13

Flat, non-palpable lesion

Answer 13

Macule

Question 14

Raised lesion < 5mm

Answer 14

Papule

Question 15

Raised dome-shaped lesion > 5mm

Answer 15

Nodule

Question 16

Raised flat-topped lesion > 5mm

Answer 16

Plaque

Question 17

Blister < 5mm

Answer 17

Vesicle

Question 18

Blister > 5mm

Answer 18

Bulla

Question 19

Pus filled blister

Answer 19

Pustule

Question 20

Any raised lesion

Answer 20

Exophytic

Question 21

Exophytic lesion arising on a broad base

Answer 21

Sessile

Question 22

Exophytic lesion arising on a stalk or pedicle that is narrower than the lesion

Answer 22

Pedunculated

Question 23

Lesion composed of multiple fronds or projections (may be sessile or pedunculated)

Answer 23

Papillary

Question 24

Thickening or hyperplasia of stratum spinosum

Answer 24

Acanthosis

Question 25

Loss of intracellular bridges and cohesion of cells of stratum spinosum

Answer 25

Acantholysis

Question 26

Edema of stratum spinosum, widening intracellular bridges

Answer 26

Spongiosis

Question 27

Hyperplasia of reticular dermis, resulting in multiple surface elevations

Answer 27

Papillomatosis