Skin infections and infestations Flashcards
What is an infection?
The pathological state resulting from the invasion of the body by pathogenic microorganisms
Invasion and multiplication of disease-causing organisms that can lead to local cellular/tissue injury.
Which bacteria normally live on our skin?
Staphylococcus epidermidis
Staph Aureus
Yeast - malassezia furfur
Other aerobic and anaerobic bacteria:
Corynebacterium
Propionbacterium
These should all be in balance
Signs of infection
Erythema - redness Hot Tender Pus - doesn't always mean infection Exudate Fever
Investigations done to check for infection
Skin swab for Microscopy, culture and sensitivities (M,C&S)
If clinically indicated:
Full blood count, ESR
U&Es, LFTs, Calcium, CRP (sign of systemic inflammation)
Skin biopsy
What is Impetigo?
A superficial skin infection. More likely to get it if you have eczema due to barrier dysfunction
Most common bacterial skin infection in children
honey crusting
Causative organisms for impetigo?
Staph A and Strep Pyogenes
Treatment of impetigo
If localised - fusidic acid or Mupirocin (If MRSA - try to restrict this so staph A doesn’t become resistant
If widespread, severe, bullous - flucloxacillin, erythromycin
Name 2 other common skin infections
Cellulitis
Erysipelas
Features of cellulitis and erysipelas
Acute onset, feeling unwell, temperature, systemic = clues to infection
Asymmetrical
Can draw around it to track progression/ response to treatment
Likely causative organisms in cellulitis/erysipelas
Streptococcus pyogenes
Staphylococcus aureus
What is the 1st choice antibiotic in severe cases of cellulitis/erysipelas?
Flucloxacillin + Benzylpenicillin
Which skin problems can occur in the lower legs?
DVT
Venous eczema
Allergic contact dermatitis - dressing etc
Necrotising faciitis - deeper infection, v unwell
If there is a suspected bacterial infection how should you manage it?
Take a swab
Start antibiotics - review after 48 hrs (check skin swab result + response to treatment). Often start broad spectrum then narrow down once sensitivities from swab are back.
If not better in a week consider a different diagnosis (if infection it will usually respond within a week)
Oedema blisters
Often caused by an acute exacerbation of oedema - tissue doesn’t have enough time to compensate
Commonly on dorsum of feet
Often erythematous - red
Can feel hot
Features of Lipodermatosclerosis
Chronic ongoing venous stasis – affects full thickness of skin
Woody/hard leg
If acute can be hot and tender. Often bilateral.