Benign skin lesions Flashcards

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1
Q

Seborrhoeic keratoses

A

Benign, but commonly referred

Warty growths, “stuck on appearance”

Can have variable appearance

Patients often have multiple +/- cherry angiomas

Generally left untreated, but if troublesome get Cryotherapy (freeze) or Curettage (scraping/cutting)

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2
Q

Name some benign skin lesions (7)

A
Seborrhoeic keratoses
Viral warts
Cysts
Dermatofibroma
Limpoma
Angioma
Pyogenic Granuloma
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3
Q

Pros and cons of cryotherapy

A

Pros: Cheap and Easy to perform “on the day

Cons: Can scar. May reoccur or fail. No pathology result.

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4
Q

What is the Sign of Leser-Trelat

A

A skin disorder characterised by the abrupt appearance of widespread seborrhoeic keratoses

Particular in younger individuals

Paraneoplastic phenomenon

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5
Q

What underlying pathology can Suborrhoeic keratoses sometimes indicate?

A

Solid organ malignancy - GI adenocarcinoma

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6
Q

What is a cyst?

A

Encapsulated lesion containing fluid or semi-fluid material

Usually firm and fluctuant

Common - affect 20% adults

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7
Q

What are the different types of cysts that exist? (5)

A
Epidermoid cyst (often wrongly called sebaceous)
Pilar cyst			
Steatocystoma
Dermoid cyst
Hidrocystoma
Ganglion cyst
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8
Q

Treatment of cysts

A

Treat with Excision

if they are inflamed or infected then:
Antibiotics
Intralesional steroids
incision and drainage

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9
Q

Dermatofibroma

A

Benign fibrous nodule, often on limbs - proliferation of fibroblasts

Cause = unknown

Pale pink/brown, firm nodule.

Dimple sign positive

usually asymptomatic

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10
Q

Limpoma

A

Benign tumour consisting of fat cells

Common

Cause = unknown

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11
Q

Angioma

A

Overgrowth of blood vessels in the skin due to proliferating endothelial cells

Generally asymptomatic. Can be unsightly or bleed

Occurs in all age groups + both sexes

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12
Q

Name 3 common types of angiomas

A

Cherry angiomas
Spider naevi
Venous lakes - dilated venules

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13
Q

Pyogenic Granuloma

A

Rapidly enlarging red/raw growth, often at a site of trauma

Bleed easily

Cause = unknown

Occur in up to 5% pregnancies

Removed by curettage + cautery (burn off)

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14
Q

What is Bowen’s disease? (Intraepidermal squamous cell carcinoma)

A

Full thickness dysplasia, entirely contained within the epidermis, no metastatic potential

Potential to become malignant (around 5%)

Irregular, scaly erythematous plaque

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15
Q

Treatment of Bowen’s disease

A

Cryotherapy (freeze)

Curettage (Lesion scraped off and heat applied to seal vessels and destroy residual cancer cells)

Photodynamic therapy

Imiquimod

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16
Q

What is photodynamic therapy? and how does it work in removing cancerous cells

A

Photochemical reaction to selectively destroy cancer cells

Topical photosensitising agent applied
Concentrates in cancerous cells

Red light applied (light colour dependant on which agent is used)

Photodymanic reaction occurs between light, photosensitiser and oxygen causing inflamation and destruction of cells

17
Q

Pros and cons of photodynamic therapy

A

Pros: Done for the patient by hospital staff. Can treat multiple areas, including those which would be hard to reach by patient. 1 or 2 treatments.

Cons: requires hospital appointments. Can be painful and scar

18
Q

What is Imiquoid?

A

Imiquimod cream is a cancer treatment and is also known by its brand name, Aldara

It is an immune response modifier - it stimulates cytokine release (results in inflammation and destruction of lesion)

Useful is surgery isn’t desired. Can cover large surface area.

Takes 6 weeks + there is significant inflammation.

19
Q

What is Acitinic keratoses?

A

Rough scaly patches on sun damaged skin

Low risk of transformation to Squamous cell carcinoma

20
Q

Treatment of Acitinic keratoses (4)

A

Cryotherapy
Curettage
Diclofenac Gel
Imiquimod

21
Q

Sun protection

A

Cover up
Avoid sun at peak hours
10am-4pm

Don’t burn and try not to tan + Avoid sunbeds

Sunscreen
- UVA & UVB protection
At least SPF 30 / 4 Star
Need to apply 2 tablespoons every 2 hours