Skin DSA Flashcards
skin fnxs
barrier tactile interaction body temp regulation sexual attractiveness immune system
skin immune fnx
cytokines and defensin production
Ag presentation via langerhans cells and dermal dendrocytes
layers of skin
epidermis
dermis (papillary and reticular)
subQ
adnexae
3 major structural units and specialized nn structures:
- pilar units
- eccrine units
- apocrine units
pilar units
hair units
pilosebaceous units and errector pili mm
eccrine units
eecrine glands and ducts
apocrine units
apocrine glands and ducts
layers of epi
stratum corneum stratum lucindum statum granulosum stratum spinosum stratum basalis
stratum corneum
corneocytes (final step in differentiation of keratinocytes differentiation)
thickest in palms and soles
stratum lucindum
only in palms and soles
stratum granulosum
keratinocytes lose their nuclei and cytoplasm appearing granular
stratum spinosum
keratinocytes become connected via desmosomes and produce lamellar bodies
langerhan cells are in this layer
basal/germinal layer
proliferating and non-proliferating keratinocytes attached to BM by hemidesmosomes
merkel cells here
apocrine glands
present deep in dermis
often at jnx of reticular dermis and subQ
melanocytes
each melanocyte will supplly about 30 keratinocytes with melanosomes