images Flashcards
1
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A
Fibroepithelial polyp
aka skin tag, acrochoordon, fibroma molle, squamous papilloma
2
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FEP
3
Q
A
epithelial inclusion cyst
filled with keratinous debris, lined by squamous epi and ganular layer
if ruptures -> foreign body giant cell rxn
4
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A
epithelial inclusion cyst
5
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A
Seborreheic keratosis
proliferation of epidermal basal cells
6
Q
A
acanthosis nigricans
7
Q
A
multiple cylindromas (papules)
8
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A
cylindromas are composed of islands of basaloid cells containing occasional ducts that fit together like pieces of a jigsaw puzzle.
9
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A
Perinasal papules and small nodules of trichoepithelioma
10
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Perinasal papules and small nodules of trichoepithelioma are composed of buds of basaloid cells that resemble primitive hair follicles
11
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A
sebaceous adenoma
look like rounded slightly yellow nodule
12
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A
Pilomatrixoma
ghost cells
13
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A
apocrine carcinoma
14
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A
hemangiomas
15
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A
hemangiomas
16
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A
hemangiomas
17
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A
errupitve xanthomas
18
Q
A
erruptive xanthomas
19
Q
A
Benign Fibrous Histiocytoma (Dermatofibroma)
20
Q
A
Solar Lentigo
21
Q
A
Melanocytic Nevus, Junctional Type
22
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A
Melanocytic Nevus, Junctional Type
23
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A
Melanocytic Nevus, Junctional Type
24
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A
Melanocytic Nevus, Compound Type
25
Melanocytic Nevus, Compound Type
26
Melanocytic Nevus, Intradermal Type
27
Melanocytic Nevus, Intradermal Type
28
Blue Nevus
29
Blue Nevus
30
Dysplastic (Clark) Nevus
31
Dysplastic (Clark) Nevus
## Footnote
–Prominent proliferation of melanocytes arranged as nests (theques) at the tips of rete ridges.
–The rete ridges with these melanocytic nests are often “bridged” (connected at their bases).
–The papillary dermis frequently has increased fibrosis (structural collagen replacing reticular fibers) – termed “fibroplasia”
32
Dysplastic Nevus
33
Malignant Melanoma
34
Malignant Melanoma
35
Actinic (Solar) Keratosis
36
Actinic (Solar) Keratosis
37
Invasive Squamous Cell Carcinoma
38
Invasive Squamous Cell Carcinoma
39
Invasive Squamous Cell Carcinoma
40
Invasive Squamous Cell Carcinoma
41
Keratoacanthoma
grows rapidly
grade 1 SCC
42
Keratoacanthoma
43
Keratoacanthoma
44
Nevoid Basal Cell Carcinoma Syndrome (Gorlin Syndrome)
45
rodent ulcer of BCC
46
nodular BCC
47
nodular BCC
48
nodular BCC
Isolated Nests (Islands) Basaloid Cells within Papillary Dermis
49
Nodular BCC
Nests separated from adjacent stroma by “clefts” (clear spaces)
peripheral pallisading
50
Sclerosing (Morpheaform) BCC
51
Sclerosing (Morpheaform) BCC
52
Superficial BCC
confused with malignant melanoma
recur b/c field defect
53
Superficial BCC
54
Dermatofibrosarcoma Protuberans
55
Dermatofibrosarcoma Protuberans
56
Dermatofibrosarcoma Protuberans
57
Dermatofibrosarcoma Protuberans
58
cutaneous T-cell lymphoma
Several erythematous plaques with scaling and ulceration are evident
Microscopically, there is an infiltrate of atypical lymphocytes that accumulates beneath and invades the epidermis.
59
Sezary syndrome is variant of T-cell lymphoma which skin involvement is manifest as a generalized exfoliative erythroderma
60
Mastocytosis
histo: numerous ovoid cells with uniform, centrally located nuclei in dermis.
Giemsa staining -\> purple, "metachromatic" granules in cyto of the mast cells.
61
Eczema =
Spongiotic Dermatitis
62
Erythema Multiforme
63
Seborrheic Dermatitis
64
Seborrheic Dermatitis
65
psoriasis
66
Lichen Simplex Chronicus
67
Lichen Planus
68
Lupus erythematosus.
69
Lupus erythematosus. Infiltrate of lymphocytes within the superficial and deep dermis, marked thinning of the epidermis with loss of normal rete ridges, and hyperkeratosis.
70
Lupus erythematosus. Infiltrate of lymphocytes within the superficial and deep dermis, marked thinning of the epidermis with loss of normal rete ridges, and hyperkeratosis.
71
Rosacea
72
Granular deposits of immunoglobulin (here IgG) and complement (C3) at dermoepidermal junction constitute a positive "band test" in lupus erythematosus.
73
Rhinophyma
end stage rosacea
74
A) pemphigus vulgaris- deposition of immunoglobulin (Dsg1 &Dsg3) in a reticular or fishnet-like pattern acompanied by suprabasalar loss of cell-to-cell adhesion (acantholysis)
B) pemphigus foliaceus- the immunoglobulin (Dsg1) deposits and acantholysis are more superficial
75
bullous pemphigoid.
Linear deposition of C' along the dermoepidermal junction in Abs bind hemidesmosomes which attach the epidermis to the lamina lucida of BM
76
Pemphigus Vulgaris
Dsg1 & Dsg3 in all desmosomes
77
Pemphigus Foliaceus
Dsg1 in superficial desmosomes
78
Bullous Pemphigoid
79
Dermatitis Herpetiformis
IgA to gliadin attacks reticulin in dermal papillae fibrils
80
Dermatitis Herpetiformis
IgA to gliadin attacks reticulin in dermal papillae fibrils
81
Dermatitis Herpetiformis
IgA to gliadin attacks reticulin in dermal papillae fibrils
82
Panniculitis
•Inflammation of the subcutaneous fatty tissue
–Septal
–Lobular
83
Verruca Vulgaris
84
Molluscum Contagiosum
85
Molluscum Contagiosum
86
Acne Vulgaris
87
Impetigo
88
Tinea
89
Tinea
90
Ichthyosis:
usually genetic abnormality leading to hyperkeratosis
noninflammatory
91
Epidermolysis Bullosa: genetic abnormalities in structural proteins leading to massive bullae
noninflammatory
92
Porphyrias: usually autosomal dominant defects in heme synthesis leading to increased intermediates somehow causing urticaria and subepidermal vesicles (especially with sun exposure
noninflammatory
93
Epidermolysis Bullosa
