Skin Changes over the Lifespan

Question 1

____ changed that occur with age and genetics and happen with everyone to some extent. ____ changes occur due to exposure or diet and varies from person to person.

Answer 1

Intrinsic
Extrinsic

Question 2

Intrinsic changes:
Decreased ____, ___ ___, ___ content, and impaired regulation of ___ ___.

Answer 2

Collagen, blood flow, lipid, cellular proliferation

Question 3

Increased ____, and decreased _____, and shortening ____ all contribute to intrinsic changes

Answer 3

ROS
anti-oxidant species
Teleported

Question 4

Extrinsic aging of skin is mainly due to ___ ___ causing dermatoheliosis. Mechanism is thought to be UV radiation directing damaging ___ and degrading ___. Cells can sometimes go into ____.

Answer 4

UV exposure
DNA
collagen
Senescence

Question 5

In this lecture, ____ means the lesion that won’t kill you, may or may not need treatment, may or may not resolve.

Answer 5

Benign

Question 6

Newborns:
Have no protective skin ____, weaker ___ -___ attachment. Normal to see peeling called ___.

Answer 6

Flora
Epidermal-dermal
Desquamation

Question 7

____ ____ ____: erythematous macules, papules, and pustules location anywhere on the body but especially the forehead, face trunk, extremities. Not the palms and soles. Not painful or itchy. Occurs within the first 3 to 4 days. Resolves on its own In a few weeks.

Answer 7

Erythema toxicum neonatorum

Question 8

Use the description below to identify the disease:

Answer 8

Transient neonatal pustular melanosis

Question 9

What disease is this:

Answer 9

Nervous simplex

Question 10

We See this skin disease in newborns but we also can see it in adults meaning bimodal incidence.

Answer 10

Milia

Question 11

Also has bimodal incidence in adults

Answer 11

Sebaceous gland hyperplasia

Question 12

Disease is caused by melanin in the epidermis rather than the dermis

Answer 12

Congenital dermal melanocytosis

Question 13

___ ____: large is 20 to 40 cm, giant is greater than 40 cm and has a small risk of transformation to metatastic melanoma

Answer 13

Congenital Melanocytic Nevus

Question 14

Childhood timeframe:
Starting to establish ___. Increased ___ ___ area to weight ratio. They have thinner skin than adults. All of this puts them at risk of ___ ___ from percutaneous absorption of substances

Answer 14

Flora
Body surface
Systemic toxicity

Question 15

What is this? Essentially a freckle.
1 to 3 mm light brown macules. Found in areas that get a lot of sun exposure. Result of increases melanin in response to UV.

Answer 15

Ephelides
Ephelis (single freckle)

Question 16

Technically a Neoplasm because they are proliferation of melanocytes. Essentially a mole.

Answer 16

Nevus (acquired)
Nevi=many

Question 17

Nevi have many subtypes including ____ Nevi and can be difficulty to differentiate from ___ without a biopsy.

Dysplastic Nevi are not ______.

Answer 17

Dysplasia
Melanoma
Pre-malignant

Question 18

Red flags that prompt you to think about melanoma versus a benign Nevus:

Answer 18

Question 19

Answer 19

Cafe au lait spots

Question 20

Adolescent:

Answer 20

Acrochordon

Question 21

____ can be mistaken for an acrochordon. Can be difficult to remove because they are attached to nerves.

Answer 21

Neurofibroma

Question 22

Answer 22

Striae (stretch marks)

Question 23

Adults:

Answer 23

Dermatofibroma

Question 24

____ ____ can look similar to dermatofibroma and is malignant. Generally is larger and will progress over time.

Answer 24

Dermatofibrosarcoma protuberans

Question 25

Technically a neoplasm because it is a proliferation of subcutaneous tissue.

Answer 25

Lipoma

Question 26

____ can be mistaken for lipomas but will have much more aggressive growth, more pain

Answer 26

Liposarcoma

Question 27

Answer 27

Pilar cyst (aka trichilemmal cyst)

Question 28

Answer 28

Epidermal (epidermoid) cyst

Question 29

Adults: bimodal incidence

Answer 29

Milia

Question 30

Increased sebaceous glands

Answer 30

Sebaceous gland hyperplasia

Question 31

Answer 31

Cherry angioma

Question 32

Answer 32

Seborrheic keratosis

Question 33

Answer 33

Dermatosis papularis nigra

Question 34

Answer 34

Lentigo

Question 35

Review:

Answer 35

Question 36

Review:

Answer 36

Question 37

Review:

Answer 37

Question 38

Question 39

Review:

Answer 39

Question 40

Review:

Answer 40