Skin Flashcards
1
Q
Name the 7 layers of the skin:
A
Stratum corneum Stratum granulosum Stratum spinosum Stratum basale Basement membrane Dermis Hypodermis
2
Q
Describe epidermis formation:
A
Cells migrate up layers, differentiating before they reach stratum corneum where are lost; changing morphology from basale, spinosum (have spines) and then to granulosum (have keratin granules) - needed to create barrier function of skin (using keratin protein)
3
Q
What do melanocytes do?
A
Sit on Basement membrane w/dendritic projections.
Deposit melanin to protect DNA/nuclei of keratinocytes from radiation.
4
Q
What stimulates Melanocytes to produce melanin?
A
Paracrine action of Melanocyte stimulating hormone from keratinocytes.
5
Q
What are langerhans cells in the skin?
A
Antigen presenting cells in epidermis
