Skin

Question 1

What are the 4 layers of the epidermis?

Answer 1

stratum basale, stratum spinous, stratum granulosum, stratum corneum

Question 2

What cells mainly make up the epidermis?

Answer 2

keratinocytes

Question 3

What happens to keratinocytes as it moves up the layers?

Answer 3

form basal layer, proliferate and move up, differentiate, drop off at corneum

Question 4

What other cells make up the epidermis?

Answer 4

melanocytes - sit on basement membrane
langerhan - antigen presenting
merkel - sit on basement membrane

Question 5

What are the names of the different keratinocytes

Answer 5

basal cell, prickle cell, granular cell, keratin

Question 6

What do keratinocytes do?

Answer 6

form a seal

Question 7

What granules do granular cells contain?

Answer 7

keratin

Question 8

What do melanocytes do?

Answer 8

produce melanin, protects keratinocytes DNA from UV damage by melanosomes

Question 9

What is a characteristic of melanocytes?

Answer 9

dendritic

Question 10

What is the process for melanin production?

Answer 10

UV light stimulates keratinocytes to product melanocyte simulation hormone which then proceed melanin

Question 11

Where is the basement membrane in skin?

Answer 11

between epidermis and dermis

Question 12

What is the dermis?

Answer 12

supportive connective tissue matrix that varies in thickness

Question 13

What is the function of the dermis?

Answer 13

maintain core temp by:

• regulating skin blood flow
• sweating
• shivering

Question 14

What is the function of skin?

Answer 14

waterproofing, thermoregulation, sensory, protection and cosmetic