Skin

Question 1

urticaria

Answer 1

type i hypersensitivity - IgE
Ag - foreign
microvascular hyperpermeability
edema - widely spaced collagen
mononuclear cells, neutrophils, eosinophils
persistent lesions - urticarial vasculitis

Question 2

acute eczematous dermatitis

Answer 2

most common contact dermatitis
red papule - ooze, crusty
ag - modified self protein
spongiosis
intracellular bridges - - stretch (edema)
edema - of dermal papillae
lymphocytes
mast cells

plaques - oozing
blisters
hyperkeratosis
acanthosis

Question 3

erythema multiforme

Answer 3

targetoid lesion

Question 4

paraneoplastic syndrome

Answer 4

seborrheic keratosis

Question 5

melanoma

Answer 5

rapid enlargement
irregular border
variegated colors
new lesions in adulthood
itching
pain

Question 6

breslow thickness

Answer 6

the distance between the upper layer of the epidermis and the deepest point of tumor penetration. The thinner the melanoma, the better the chance of a cure.

Question 7

auspitz sign

Answer 7

psoriasis

Auspitz’s sign is the appearance of punctate bleeding spots when psoriasis scales are scraped off, named after Heinrich Auspitz

Question 8

CTLA4 and PD

Answer 8

antibodies that inhibit endogenous inhibitors of immune responses