Skin Flashcards
_____ is the most convincingly demonstrated infectious cause of Steven-Johnson Syndrome
Mycoplasma pneumoniae
_____ are the most common precipitants of SJS and TEN.
Drugs (sulfonamides, NSAIDs, antibiotics, anticonvulsants)
The skin lesions in SJS are typically more widespread than in erythema multiforme and are accompanied by involvement of ≥ 2 mucasal surfaces, namely _____.
eyes oral cavity upper airway GI tract anogenital mucosa
Early Signs of SJS
burning sensation
edema
erythema of lips and buccal mucosa
Late Signs of SJS
bullae
ulceration
hemorrhagic crusting
_____ is minimal to absent in SJS.
skin tenderness
_____ is the most severe disorder in the clinical spectrum of the disease, involving constitutional toxicity and extensive necrolysis of the mucous membranes and > 30 % of the body surface area.
Toxic Epidermal Necrolysis
Management of SJS is _____.
supportive and symptomatic
In SJS, systemic antibiotics are indicated for _____ because infection is the leading cause of death.
urinary or cutaneous infections suspected bacteremia (S. aureus, P. aeruginosa)
_____ should be considered early in the course of SJS.
IVIG
_____ is characterized by the infection and inflammation of loose connective tissue, with limited involvement of the dermis and relative sparing of the epidermis.
Cellulitis
_____ are the most common etiologic agents of cellulitis.
Streptpcoccus pyogenes
Staphylococcus aureus
Cellulitis due to _____ tends to be more localized and may suppurate.
S. aureus
Cellulitis due to _____ tend to spread more rapidly and may be associated with lymphangitis.
S. pyogenes
Treatment of cellulitis in an infant or child ≤ 5 y.o. should provide coverage for _____.
S. pyogenes
S. aureus
H. influenzae Type B
S. pneumoniae
Cellulitis is treated with _____.
Oxacillin
Nafcillin
_____ is a subcutaneous tissue infection that involves the deep layer of superficial fascia but largely spares adjacent epidermis, deep fascia and muscle.
Necrotizing Fasciitis
The majority of cases of necrotizing fasciitis are _____ in nature.
polymicrobial
The organisms most commonly associated with necrotizing fasciitis are _____.
S. aureus Streptococcal species Klebsiella species E. coli Anaerobes
The most fulminant cases of necrotizing fasciitis are usually caused by _____.
S. pyogenes
Early clinical findings of _____ include ill-defined cutaneous erythema and edema that extends beyond the area of erythema.
Necrotizing Fasciitis
Vesiculation or bulla formation, ecchymoses, crepitus, anesthesia and necrosis are ominous signs indicative of advanced _____.
Necrotizing Fasciitis
Definitive diagnosis of necrotizing fasciitis is made by _____.
surgical exploration
Necrotizing fasciitis is treated with _____.
early supportive care
surgical debridement
parenteral antibiotics
