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Host and Defense PMO > Skin! > Flashcards

Skin! Flashcards

1
Q

Impetigo

A

bacterial infection of the epidermis

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2
Q

Cellulitis

A

infection of the dermis

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3
Q

folliculitis

A

bacterial infection of appendages

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4
Q

What does stratum corneum do?

A

prevent water loss, chemical entry

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5
Q

What does dermis do?

A

It is tough, repels physical insults

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6
Q

What does subcutaneous fat do?

A

protects underlying structures from injury

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7
Q

Bacterial infections of skin

A

Impetigo

Folliculitis

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8
Q

Viral infections of skin

A

Herpesvirus
molluschi contagiosi
Verruca vulgaris

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9
Q

Fungal infections of skin

A

Tinea versicolor
Tinea corporis
Deep fungal infection

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10
Q

Infestation

A

Scabies

Myiasis

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11
Q

Normal skin flora

A

Aerobic cocci, aerobic and anaerobic coryneform bacteria, gram negative bacteria, yeast

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12
Q

Infectious panniculitis/fascitis

A

bacterial infection of fat layer/fascia

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13
Q

Most cutaneous infections are caused by

A

Staph aureus

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14
Q

Destruction of follicle wall, PMNs. What it is?

A

Folliculitis- treat with antibacterial soap, topical or systemic antibiotics

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15
Q

papovavirus

A

warts

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16
Q

DNA viruses infect

A

keratinocytes

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17
Q

RNA viruses infect

A

CD4 helper T cells

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18
Q

Viral infections of the epidermis

A

Molluschi contagiosa
Herpesvirus
Verruca

19
Q

What is an appendage viral infection of skin?

A

Folliculitis from herpes virus

20
Q

A positive interpretation of the Tzanck smear requires

A

identification of multi-nucleated keratinocytes

-peripheral margination of chromatin (ground glass appearance)

21
Q

If you have a negative reading of a Tzanck smear, what should you do?

A

It is probably still herpes. Scrape again. It if pretty specific and sensitive

22
Q

How does Herpes Varicella Zoster happen?

A

reactivation of varicella zoster virus (chicken pox) from the dorsal root ganglion. Travels down nerve into skin. Usually in immunosuppressed and old people. Usually unilateral in one dermatome

23
Q

Double stranded DNA viruses:

A

Herpes simplex 1 and 2
Varicella (chicken pox, herpes)
Cytomegalo virus
Epstein-Barr (infectious mono)

24
Q

Herpetic whitlow

A

Herpes in your digits

25
Q

Eczema herpeticum

A

life threatening infection of a pre-existing skin rash, usually atopic dermatitis

26
Q

Herpes Zoster

A

Shingles or chickenpox

27
Q

Where does oral herpes occur?

A

keratinized tissue (palate, gingiva, tongue)

28
Q

Oral Hairy Leukoplakia

A

Epstein-Barr virus (EBV)
Common in HIV patients, immunosuppressed, smokers
Usually don’t have to treat. Or systemic antivirals, (acyclovir and brothers)

29
Q

Henderson-patterson bodies

A

molluscum bodies. (Pox virus causes red inclusions). Little kids and STD. Cause umbellicated spots

30
Q

What are the signs of HPV

A

Thick granular cell layer with koilocytes

31
Q

What are the HPVs of Verruca vulgaris

A

HPV 1,2,4, 27, 57, 63

32
Q

What are the HPVs of Verruca Plantaris?

A

HPV 1,2,4,27,57

33
Q

What are the HPVs of Verruca plana

A

HPV 3,10,28,41

34
Q

What are the HPVs of genital warts or condyloma?

A

HPV 6,11

35
Q

Fungal infections of the epidermis/stratum corneum

A

Tinea versicolor

Dermatophytosis

36
Q

If a rash is scaly,

A

do a KOH preparation to make sure it isn’t fungus (if it is, steroids will make it worse)

37
Q

What causes Tinea Versicolor

A

Pityrosporum orbiculare

38
Q

Dermatophyte infection

A

Can only survive on dead keratin or hair and nails (aka ringworm)

39
Q

What do you see with paracoccidoidomycosis?

A

Mariner’s wheel

40
Q

What is the key risk factor for deep fungal infections?

A

Neutropenia (immunosuppression is big too)

41
Q

Common fungal deep infections

A

Candidiasis
Aspergillosis
(These can be life threatening)

42
Q

Where does a scabies mite lay eggs?

A

In the stratum corneum (circle of hebra: wrists, hands, genital region, axilla)

43
Q

Botflies are an example of

A

Myiasis

Host and Defense PMO (8 decks)

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