Skeletal system Flashcards

1
Q

Bone function

A
  • support
  • protection
    movement
  • mineral reservoir
  • calcium, phosphate, magnesium
  • blood calcium homeostasis
  • hematopoiesis
  • myeloid tissue
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2
Q
  • osteoblast
A
  • originate from osteogenic stem cells * secrete osteoid * active during bone mineralization
    bone-forming cell,
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3
Q

osteocyte

A

manufacture type I collagen
mature bone cells

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4
Q

osteoclast

A

originate from fusion of several precursor cells
* active during bone resorption
resorb or break down bone

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5
Q

Osteogenesis

A
  • the process by which calcification occurs from combined osteoblastic and
    osteoclastic activity
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6
Q

bone formation
Intramembranous ossification

A

bone formation from a fibrous membrane model
babys soft spot itll get harder
* osteogenic stem cells differentiate to osteoblasts
* secrete ground substance
* collagen fibers embed in matrix
* calcium salts deposit in this framework

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7
Q

Bone formation
* endochondral ossification

A

bone formation from a cartilage model

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8
Q

Bone growth and resorption

A
  • remodeling is a life-long process
  • opposing processes act in concert at different rates depending upon our
    stage of life
  • adaptive
  • pathological
    start with hemopoietic bone cells
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9
Q

Bone repair

A

initiated by blood vessel damage
* developing fracture hematoma recruit cells for bone repair
fibrocartilaginous callus forms then a body callus forms
and “splints” the ends
* bone is remodeled

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10
Q

acquired bone disorders

A
  • fractures
  • rickets
  • bone tumors
  • abnormal curvature
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11
Q

Rickets

A
  • a bone disease of children
  • insufficiency or inefficiency of vitamin D
  • developing bones are demineralized
  • “bowed legs”
  • other skeletal deformities
  • bone pain
  • tests
  • calcium, vitamin D, PTH, alkaline phosphatase
  • treatment
  • diet, bracing, surgical correction
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12
Q

osteogenic sarcoma

A

bone tumor
a malignant primary neoplasm of bone
* arises in the metaphysis
* highest incidence in adolescents
* variable gross appearance
* osteolytic
* osteoblastic
* diagnosed using bone scan, biopsy
* treatment
* surgical removal
* chemotherapy

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13
Q

Classifications of Joints
STRUCTURAL

A

**fibrous
located between facial bones and between the bones in the adult skull.
- syndesmoses -two long bones connected by inter-osseous ligament
-sutures -adjacent flat bones interlocked by fibrous
tissue, which is ossified in later life- baby head soft spot
-gomphoses -Fibrous tissue between tooth root and mandible

  • cartilaginous
    - synchondroses-articulating bones joined by HYALINE cartilage -1st rib, epipyseal plate in children
    - symphyses-articulating bones joined by FIBROCARTILAGE- symphysis pubis and vertebral disks
  • synovial (uni-, bi and multi-axial joints)
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14
Q

Classifications of Joints FUNCTIONAL

A
  • synarthroses (immoveable)
  • amphiarthroses (limited movement)
  • diarthroses (freely moveable)
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15
Q

HYALINE

A

slippery and smooth which helps your bones move smoothly past each other in your joints.
AT THE END OF BONE JOINT

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16
Q

fibrocartilage

A

tough, very strong tissue found predominantly in the intervertebral disks and at the insertions of ligaments and tendo

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17
Q

Synovial Joints

A

cover by a Joint Capsule made with Synovial Membrane + fibrous capsule = articular capsule

  • Articular cartilage
  • Joint cavity
  • Menisci (articular disks)
  • Ligaments
  • Bursae

most moveable joint in the body

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18
Q

Types of Synovial Joints
Uniaxial:

A

movement on one axis and in one plane
* Hinge joints - elbow
* Pivot joints - wrist

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19
Q

Types of Synovial Joints
Biaxial:

A

movement around two perpendicular axes in two
perpendicular planes
* Saddle joints -thumb
* Condyloid (ellipsoidal) joints - wrist

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20
Q

Types of Synovial Joints
Multiaxial:

A

movement around three or more axes and in three
or more planes
* Ball and Socket joints
* Gliding joints

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21
Q

Angular

A

Flexion or Extension or Hyperextension
* Flexion decreases the angle between bones
* Extension increases the angle between bones
* Hyperextension stretches an extended part beyond the anatomical position
* Plantar Flexion: Foot stretched down and back (extension)
* Dorsiflexion: Foot stretched upwards

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22
Q

Abduction or Adduction

A

part moved away from median = abduction
* part moved toward median = adduction

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23
Q

Circular

A

Rotation or Circumduction
* Bone pivots on own axis = Rotation
* Distal part of bone moves in a circle = Circumduction

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24
Q

Supination or Pronation

A

Palm of hand faces up = Supination
* Palm of hand facing down = Pronation

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25
Gliding
one bone slides over another
26
Special Movements
* Inversion: Sole of foot inward * Eversion: Sole of foot outward * Protraction: part moves forward = protraction * Retraction: part moves back = retraction * Elevation: joint moves up * Depression: joint moves down
27
Osteoarthritis
Thinning and degradation of articular cartilage * Wear & tear degenerative joint disease
28
Rheumatoid Arthritis (RA)
* autoimmune: deposits of antigen-antibody complexes in synovial membranes
29
Gouty arthritis
* High blood levels of uric acid * Deposits as sodium urate crystals in synovial joints * Causes inflammation forms tophi eat less beer and meat
30
* Bursitis
* Inflammation of the bursa
31
* Dislocations
Traumatic injuries * Articular surfaces of bones no longer is proper contact
32
Sprain
* Traumatic injury to ligaments surrounding joint
33
calcium regulation in the body
Blood calcium levels are regulated by parathyroid hormone (PTH), which is produced by the parathyroid glands. PTH is released in response to low blood calcium levels. It increases calcium levels by targeting the skeleton, the kidneys, and the intestine Thyroid releases calcitonin to stimulate ca deposit in skeletal, reduces in intestines' and kidneys
34
The skeleton is subdivided into two major divisions
axial skeleton -head, neck, back and chest, paranasal sinuses and appendicular skeleton- everything else bones in your shoulders, pelvis and limbs, including your arms, hands, legs and feet.
35
synarthrosis
joint in which no significant movement occurs The joints between cranial bones are synarthroses, commonly called sutures (
36
Structure of long bones
1. Diaphysis, or shaft— hollow tube of hard compact bone 2. Medullary cavity— hollow space inside the diaphysis that contains yellow marrow 3. Epiphyses— ends of the bones made of spongy bone that contains red bone marrow 4. Articular cartilage— thin layer of hyaline cartilage that covers each epiphysis; provides a smooth cushion 5. Periosteum— strong, fibrous membrane covering bone everywhere except at joint surfaces surrounds the diaphysis 6. Endosteum— thin membrane that lines medullary cavity
37
Structure of flat bones
1. Spongy bone layer sandwiched between two compact bone layers sternum, ribs and cranial bones
38
Endochondral ossification
cartilage models gradually replaced by calcified bone common in long bones some bones hae 2 ossification centers
39
Intramembranous ossification
fibrous membranes are ossified into hard bone plates; fontanels are soft, not-yet-ossified regions bone is a connective tissue so it is made up of living cells and a non living matrix collagen gives bones their flexibility
40
Atlas and axis
first two cervical vertebrae form a unique pivoting structure
41
Age differences
1. Bones enlarge and become more ossified until maturity at age 25 2. Bones actively remodel (dissolve and rebuild) in middle adulthood 3. Bones become less dense during elderly years
42
Osteoporosis
Characterized by loss of calcified bone matrix stop smoking and drinking caused by no calcium and Vit D in diet eat lots of greens and salmon to maintain bone health bone health - weight lifting increase bone density by walking Regular exercise is recommended to help prevent osteoporosis. Estrogen helps protect against osteoporosis.
43
amphiarthrosis
joint in which only slight movement is possible the joint between the two pubic bones
44
Diarthroses
freely movable joints
45
hematopoiesis
the production of blood cells in children in happens in long bone that has red bone marrow in adults this changes to yellow bone marrow the only place adults have red bone marrow is skull, ribs vertebra and pelvis
46
Four major types, according to overall shape of the bone
1. Long— example: humerus (arm) 2. Short— example: carpals (wrist) 3. Flat— example: frontal (skull) 4. Irregular— example: vertebrae (spinal bones) 5. Some also recognize a sesamoid (round) bone category— example: patella (kneecap
47
While preparing patients for a bone scan
let them know radioactive dyes will be injected before the bone scan used to diagnose bone infections
48
Fontanelles are
tough membranes that have not yet ossified allow the infant's skull to be moldable allow the infant's skull to be moldable to help the head pass through the birth canal more easily during childbirth.
49
What lines the holes of spongy bones
Endosteum cancellous, or spongy, bone.
50
Paget's disease
bones become enlarged, deformed, and weak treated by surgical remodeling of bones
51
Osteogenesis imperfecta
causes fragile bones from birth Braces help prevent bone deformities in people who have osteogenesis imperfecta.
52
foramen magnum
large opening at the base of the occipital bone
53
temporal bone
Lower sides of the skull are formed by the temporal bones. external meatus runs through the temporal bone
54
Parietal bones
top and sides of the skull
55
zygomatic bones
prominence of the cheeks.
56
ethmoid bone
forms floor of the cranium located between the sphenoid bone and the nasal bones.
57
Ulna
medial bone of the forearm
58
Metacarpals
form the palm of the hand.
59
clavicle
sternum and scapula.
60
Scapula
thin, flat bone that is commonly called the shoulder blade humerus joins with the scapula and the bones of the forearm.
61
Calcaneus
heel bone, is the largest tarsal bone Metatarsals form the front of the foot. there are 5 in each foot The bones of the toes are phalanges
62
Ligaments
hold bones together cord like
63
hyoid bone
which anchors the tongue, part of the axial skeleton which has 80 bones total bones in the body 206
64
Osteons
fundamental units of compact bone
65
Canaliculi
small canals that run perpendicular to the central canal.
66
Another name for osteogenesis is
ossification
67
part of the orbit
. Maxilla Sphenoid Frontal
68
pelvic girdle
Ilium Ischium Pubic bone
69
Bone density can be increased by
brisk walking.
70