skeletal surveys Flashcards
why are skeletal surveys performed
to detect lesions, latent pathology, pathological fx or traumatic fxs.
what are the clinical indications that can justify having a skeletal survey?
- pagets disease
- skeletal dysplasia
- NAI in children
- multiple myeloma
- oncology for metastasis
describe what pagets disease, describe its 3 phases and how it appears radiographically
its a disease that disrupts the replacement of old bone tissue with new bone tissue. Lytic phase, mixed phase, sclerotic bone calcification phase. lytic= osteoclasts rapidly break down bone. Mixed= osteoclasts are still resorbing bone, and osteoblasts are creating new bone. sclerotic calcification= the new bone creation is simisalr to spongy bone and calcifies, the bones can become deformed, overgorwn, bowed and break easily. on xray it looks like honeycomb (spongy bone) or can look dense and sclerotic in places. can be widespread.
common places for pagets diseasae
in pelvis, skull, spine and legs
clinical features that a person has pagets
bone pain, obvious deformity, swelling, deafness, spinal cord stenosis
what is multiple myeloma
a cancer of plasma cells inside the bone marrow
what does MM do and what can it lead to
eat away at bone and can lead to diffuse osteopenia/osteoporosis usually in pelvis, skull, spine, ribs. it can lead to renal failure, infection, pathological fx, local pathologies, spinal cord compression.
median age 68men-70women
another characteristic of MM
endosteal scalloping. where plasma cells take over forcing osteoclasts to the edge of medullary cavity and starts resorping bone and eating away at the edges.
what is skeletal dysplasia
affects bone and cartilage development can result in dwarfism. most common dwarf is achondroplasia
types of skeletal dysplasia (theat are detected invitro)
(over 200) achondroplasia. osteogenesis imperfecta (brittle bone disease)
whats a more serious type of dysplasia
osteogenesis imperfecta
what is achondroplasia
is a short limbed dwarfism resulting in early ossification of epiphyseal plates of long bones and skull
what type of osteogenesis imperfecta is teh most serious
type 2. (type 1 not detecred until child walks, least serious)
characterisitics of osteogensis imperfecta
fx, small thorax, abscence of a limb, duplication of fingers or toes.
common site of metastasis
spine, skull, pelvis, chest