Skeletal Muscle and Nerve Tissue Flashcards

1
Q

Makes up muscle cells

A

myofibrils; chains of sarcomeres (contractile unit) linked together form one fiber; surrounded by endomysium

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2
Q

Makes up a fascicle

A

groups of myofibers (muscle cells) surrounded by perimysium

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3
Q

Makes up a muscle

A

groups of fascicles surrounded by epimysium

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4
Q

Makes up myosin (thick filaments)

A

2 heavy chains with globular heads (have actin binding site with ATPase domains) and 2 light chains

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5
Q

What holds myosin in place

A

Titin proteins connected to the Z disc

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6
Q

Makes up sarcomere

A

actin and myosin

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7
Q

Makes up actin

A

F-actin monomers; form double stranded chains

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8
Q

Nebulin

A

determines the length of the actin filament

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9
Q

Role of tropomyosin in actin

A

wrap around the actin strands

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10
Q

Role of troponin in actin

A

sits on top of the tropomyosin and covers the myosin binding sites

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11
Q

M-line

A

attachment site for myosin

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12
Q

Z-disc/line

A

separates sarcomeres and is the attachment site for actin and titin

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13
Q

H-band

A

space on each side of M line with no actin present

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14
Q

A-band

A

distance from end of myosin head to opposite myosin head (overlap in middle)

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15
Q

I-band

A

space on either side of Z disc without myosin

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16
Q

How does muscle contraction occur

A

Ca2+ is released from the SR which binds troponin causing a conformational change; the actin binding sites are then accessible to the myosin heads

17
Q

Sarcolemma

A

Membrane around each muscle cell

18
Q

Transverse (T) tubules

A

penetrates muscle class to deliver electrical impulses from Sarcolemma into the cell

19
Q

Sarcoplasm

A

cytoplasm of muscle cell

20
Q

Sarcoplasmic reticulum

A

tubular system acting as smooth ER; terminal cistern are flattened SR space on each side of T tubule

21
Q

Triad

A

T tubule and the 2 terminal cisternae attached

22
Q

End feet

A

connect T tubule with the SR for Ca release

23
Q

Neuromuscular spindle apparatus role

A

Reflexive response to prevent overstretching of a muscle

24
Q

Extrafusal muscle fibers

A

contract the muscle

25
Q

Intrafusal muscle ribers

A

sense length and rate of change of the muscle

26
Q

1a sensory nerve fibers

A

A-fferent (sensory) innervation of the intrafusal fibers

27
Q

gamma-motor nerve fibers

A

E-fferent innervation of intrafusal fibers

28
Q

Schwann Cells

A

surround axon creating myelin sheath in PNS; wraps around one part of the axon

29
Q

Oligodendrocyte

A

Surrounds axon creating myelin sheath in CNS; wraps around MANY axons