Bone Histology

Question 1

Mesenchymal origin, found in inner periosteum and endosperm, and give rise to osteoblasts

Answer 1

Osteoprogenitor cells

Question 2

epithelial-like cells with cuboidal or columnar morphology; deposit osteoid for mineralization; have strong cytochemical reaction for AlkPhos

Answer 2

Osteoblasts

Question 3

Osteoblasts trapped inside the lacunae with osteoid matrix; highly branched that have complicated communication; MUST be alive for long life of bone matrix

Answer 3

Osteocytes

Question 4

Derived from the monocyte-macrophage lineage (not osteoprogenitor cells); generate secluded acidic environment for bone resorption (H+ ATPase); Howship’s lacuna

Answer 4

Osteoclasts

Question 5

outer layer of compact bone; key for nutritional support of osseous tissue and houses osteoprogenitor cells for growth and repair

Answer 5

Periosteum

Question 6

contains osteoprogenitor cells and osteogenic layer

Answer 6

inner layer of periosteum

Question 7

rich in blood vessels and nerves; fibroblasts and collagen fibers, and Sharpey’s fibers (anchoring collagen)

Answer 7

outer layer of periosteum

Question 8

longitudinal vascular channel that houses capillaries and post capillary venues; in the center of osteons

Answer 8

Haversian canal

Question 9

transverse (horizontal) vascular channels that connect Haversian canals

Answer 9

Volkmann’s canal