Skeletal cell anatomy Flashcards

1
Q

What is the sarcolemma?

A

the cell membrane

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2
Q

What structures are continuous with the sarcolemma and extend into the cell/fiber?

A

Transverse tubules

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3
Q

What is the sarcoplasmic reticulum? What are its two divisions?

A

Tubular network that surrounds myofibrils

Made up of Cisternae and Triads

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4
Q

What are cisternae? Where are they? What do they do?

A

Large chambers of Sarcoplasmic reticulum
on either side of T-tubules
Store Calcium ions

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5
Q

What are Triads? Where are they?

A

part of sarcoplasmic reticulum encircling the myofibril

alongside (flanking) the cisternae

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6
Q

How are myofibrils arranged?

A

into sarcomeres

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7
Q

What makes up of myofibril?

A

microfilaments

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8
Q

What are the two contractile proteins?

A

Actin and Myosin

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9
Q

Which contractile protein is the Thin filament?

A

Actin

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10
Q

What is Actin bound to?

A

Bound to Z disc

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11
Q

What is Myosin bound to?

A

Z disc and M line

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12
Q

What does Nebulin do?

A

Secures Actin to Z disc

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13
Q

What does Titin do?

A

Secures Myosin to both Z disc and M line

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14
Q

What are the two regulatory proteins? Where are they found?

A

Troponin and Tropomyosin

Found on Actin

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15
Q

What does tropomyosin do?

A

block the myosin head binding site on Actin

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16
Q

What does troponin do?

A

binds Ca++, causing conformational change to move tropomyosin

17
Q

What holds myosin in place?

A

titin

18
Q

what holds actin in place?

A

nebulin

19
Q

What makes up the M line?

A

Myomesin

20
Q

What is bound to the M line?

A

Myosin (secured by titin)

21
Q

What is bound to the Z disc?

A

Actin (nebulin) and Myosin (titin)

22
Q

What does dystrophin do? What is the point of this protein?

A
connects actin (thin) filaments to sarcolemma.
helps transmit muscle tension to the muscle tendon