Sjukdomar och ak Flashcards
1
Q
APS (autoimmunt polyglandulärt syndrom 1 eller 2)
A
tryptofanhydroxylas, 21-hydroxylas, SCC, 17-α-hydroxylas
2
Q
DM typ 1
A
GAD65, IA2, ZnT8, IAA
3
Q
LADA
A
GAD65, IA2, ZnT8, IAA
4
Q
Graves sjukdom
A
TRAK, TPO, TG
5
Q
autoimmun tyreoidit (Hashimotos tyreoidit)
A
TPO, TG
6
Q
Mb Addison
A
21-hydroxylas
7
Q
autoimmun ovariell insufficiens
A
SCC (side-chain cleavage enzyme), 17-α-hydroxylas
8
Q
AIH-1
A
glatt muskel (VGT), F-aktin, dsDNA, SLA/LP, SSA/Ro52
9
Q
AIH-2
A
LKM-1 (ev LKM-3), LC-1
10
Q
autoimmun atrofisk gastrit
A
parietalceller, IF
11
Q
celiaki
A
transglutaminas, deamiderat gliadin
12
Q
hepatit C
A
glatt muskel, M2, LKM-1, RF
13
Q
Mb Crohn
A
ASCA
14
Q
PBC
A
M2, gp210, sp100, PML, glatt muskel
15
Q
PSC
A
pANCA (elastas, katepsin G, lysozym, laktoferrin, BPI)
16
Q
ulcerös kolit
A
pANCA (elastas, katepsin G, lysozym, laktoferrin, BPI)
17
Q
anti-laminin-gamma-1-pemfigoid
A
laminin-gamma-1, BP180, BP230
18
Q
bullös pemfigoid
A
BP180, BP230
19
Q
dermatitis herpetiformis
A
transglutaminas, deamiderat gliadin
20
Q
epidermolysis bullosa aquisita (EBA)
A
kollagen VII
21
Q
IgA-pemfigus/linjär IgA-dermatos
A
BP180
22
Q
paraneoplastisk pemfigus
A
envoplakin, periplakin, desmoplakin 1, desmoplakin 2, BP230
23
Q
pemfigoides gestationis
A
BP180, BP230
24
Q
pemfigus foliaceus
A
desmoglein 1
25
pemfigus vulgaris
desmoglein 1, desmoglein 3
26
slemhinnepemfigoid
BP180, laminin 332
27
förvärvad C1-inhibitorbrist
komplementfunktion
28
hereditärt angioödem
komplementfunktion
29
antisyntetassyndrom
Jo-1, OJ, EJ, PL-7, PL-12
30
dermatomyosit
Mi-2α, Mi-2β, SAE1, TIF1γ, MDA5, NXP2/MJ
31
nekrotiserande myopati (INMN)
SRP, HMGCR
32
polymyosit
Mi-2α, Mi-2β, SRP
33
polymyosit/skleros-overlapsyndrom
Ku, PM-Scl75, PM-Scl100
34
limbisk encefalit
NDMAR, AMPAR, GABABR, LGI-1, CASPR2, DPPX, GAD65, GFAP, Hu, PNMA/Ma2, mGluR5
35
hjärnstamsencefalit
Ri, PNMA2/Ma2
36
encefalomyelit
Hu, amfifysin, CV2
37
cerebellär degeneration
Yo, PCA2, DNER/Tr, ITPR1, CARP, AHRGAP26, Zic4, SOX1, GAD65, mGluR1, VGCC
38
opsoklonus-myoklonussyndrom
Ri
39
Lambert-Eatons myastena syndrom (LEMS)
SOX1, VGCC, PCA2
40
Morvans syndrom, neuromyotoni
CASPR2
41
Stiff person syndrome
GAD65, amfifysin
42
sensorisk neuropati
Hu, CV2, amfifysin
43
paraneoplastisk retinopati (CAR)
recoverin
44
ADEM
MOG
45
Guillain-Barrés syndrom, Miller-Fishers syndrom, Bickerstaff-encefalit, AIDP
glykolipider, gangliosider (GM1, GD1a/b, GT1a, GQ1b, GD3, GalC, GM2, SGPG)
46
Myastenia Gravis
AchR, MuSK, titin (vid tymom)
47
MS
MBP, (MOG)
48
NMOSD
AQP4, MOG
49
polyneuropati med M-komponent
MAG
50
idiopatisk membranös nefropati
PLA2R
51
membranoproliferativ glomerulonefrit
C1q
52
APS (antifosfolipidsyndrom)
kardiolipin, β2-GP1, lupus antikoagulans
53
hypokomplementärt urtikaria-vaskulitsyndrom (HUVS)
C1q
54
JIA
H-ANA, CCP
55
MCTD
snRNP (ffa RNP70), Sm/RNP, SSA/Ro52, K-ANA
56
RA
RF, CCP
57
Sjögrens syndrom
SSA/Ro52, SSA/Ro60, SSB, K-ANA
58
SLE
dsDNA, C1q, Sm, snRNP, ribosomalt P, nukleosomer, histoner, SSA, SSB, Ku, H-ANA, PCNA
59
systemisk skleros
snRNP, Scl-70, Ku, NOR90, PDGFR, SSA/Ro52
60
systemisk skleros (diffus/dcSSc)
Scl-70, Ku, fibrillarin, RP11, RP155, N-ANA
61
systemisk skleros (begränsad/lcSSc/CREST)
CENP-A/B, To/Th, NOR90, C-ANA, centromerer, ND
62
anti-GBM-vaskulit (Goodpastures sjukdom)
GBM
63
eosinofil GPA (Churg-Strauss syndrom)
MPO, PR3
64
GPA (Wegeners sjukdom)
PR3, (MPO)
65
MPA
MPO, (PR3)
66
tryptofanhydroxylas, 21-hydroxylas, SCC, 17-α-hydroxylas
APS (autoimmunt polyglandulärt syndrom 1 eller 2)
67
GAD65, IA2, ZnT8, IAA
DM typ 1
68
GAD65, IA2, ZnT8, IAA
LADA
69
TRAK, TPO, TG
Graves sjukdom
70
TPO, TG
autoimmun tyreoidit (Hashimotos tyreoidit)
71
21-hydroxylas
Mb Addison
72
SCC (side-chain cleavage enzyme), 17-α-hydroxylas
autoimmun ovariell insufficiens
73
glatt muskel (VGT), F-aktin, dsDNA, SLA/LP, SSA/Ro52
AIH-1
74
LKM-1 (ev LKM-3), LC-1
AIH-2
75
parietalceller, IF
autoimmun atrofisk gastrit
76
transglutaminas, deamiderat gliadin
celiaki
77
glatt muskel, M2, LKM-1, RF
hepatit C
78
ASCA
Mb Crohn
79
M2, gp210, sp100, PML, glatt muskel
PBC
80
pANCA (elastas, katepsin G, lysozym, laktoferrin, BPI)
PSC
81
pANCA (elastas, katepsin G, lysozym, laktoferrin, BPI)
ulcerös kolit
82
laminin-gamma-1, BP180, BP230
anti-laminin-gamma-1-pemfigoid
83
BP180, BP230
bullös pemfigoid
84
transglutaminas, deamiderat gliadin
dermatitis herpetiformis
85
kollagen VII
epidermolysis bullosa aquisita (EBA)
86
BP180
IgA-pemfigus/linjär IgA-dermatos
87
envoplakin, periplakin, desmoplakin 1, desmoplakin 2, BP230
paraneoplastisk pemfigus
88
BP180, BP230
pemfigoides gestationis
89
desmoglein 1
pemfigus foliaceus
90
desmoglein 1, desmoglein 3
pemfigus vulgaris
91
BP180, laminin 332
slemhinnepemfigoid
92
komplementfunktion
förvärvad C1-inhibitorbrist
93
komplementfunktion
hereditärt angioödem
94
Jo-1, OJ, EJ, PL-7, PL-12
antisyntetassyndrom
95
Mi-2α, Mi-2β, SAE1, TIF1γ, MDA5, NXP2/MJ
dermatomyosit
96
SRP, HMGCR
nekrotiserande myopati (INMN)
97
Mi-2α, Mi-2β, SRP
polymyosit
98
Ku, PM-Scl75, PM-Scl100
polymyosit/skleros-overlapsyndrom
99
NDMAR, AMPAR, GABABR, LGI-1, CASPR2, DPPX, GAD65, GFAP, Hu, PNMA/Ma2, mGluR5
limbisk encefalit
100
Ri, PNMA2/Ma2
hjärnstamsencefalit
101
Hu, amfifysin, CV2
encefalomyelit
102
Yo, PCA2, DNER/Tr, ITPR1, CARP, AHRGAP26, Zic4, SOX1, GAD65, mGluR1, VGCC
cerebellär degeneration
103
Ri
opsoklonus-myoklonussyndrom
104
SOX1, VGCC, PCA2
Lambert-Eatons myastena syndrom (LEMS)
105
CASPR2
Morvans syndrom, neuromyotoni
106
GAD65, amfifysin
Stiff person syndrome
107
Hu, CV2, amfifysin
sensorisk neuropati
108
recoverin
paraneoplastisk retinopati (CAR)
109
MOG
ADEM
110
glykolipider, gangliosider (GM1, GD1a/b, GT1a, GQ1b, GD3, GalC, GM2, SGPG)
Guillain-Barrés syndrom, Miller-Fishers syndrom, Bickerstaff-encefalit, AIDP
111
AchR, MuSK, titin (vid tymom)
MG
112
MBP, (MOG)
MS
113
AQP4, MOG
NMOSD
114
MAG
polyneuropati med M-komponent
115
PLA2R
idiopatisk membranös nefropati
116
C1q
membranoproliferativ glomerulonefrit
117
kardiolipin, β2-GP1, lupus antikoagulans
APS
118
C1q
hypokomplementärt urtikaria-vaskulitsyndrom (HUVS)
119
H-ANA, CCP
JIA
120
snRNP (ffa RNP70), Sm/RNP, SSA/Ro52, K-ANA
MCTD
121
RF, CCP
RA
122
SSA/Ro52, SSA/Ro60, SSB, K-ANA
Sjögrens syndrom
123
dsDNA, C1q, Sm, snRNP, ribosomalt P, nukleosomer, histoner, SSA, SSB, Ku, H-ANA, PCNA
SLE
124
snRNP, Scl-70, Ku, NOR90, PDGFR, SSA/Ro52
systemisk skleros
125
Scl-70, Ku, fibrillarin, RP11, RP155, N-ANA
systemisk skleros (diffus/dcSSc)
126
CENP-A/B, To/Th, NOR90, C-ANA, centromerer, ND
systemisk skleros (begränsad/lcSSc/CREST)
127
GBM
anti-GBM-vaskulit (Goodpastures sjukdom)
128
MPO, PR3
eosinofil GPA (Churg-Strauss syndrom)
129
PR3, (MPO)
GPA (Wegeners sjukdom)
130
MPO, (PR3)
MPA
