sjorgens

Question 1

What is sjogrens syndrome?

Answer 1

An autoimmune exocrine dysfunction
DRY!!!

Question 2

Typical presentation and risk factors of Sjogren syndrome? (4)

Answer 2

• Can be primary or secondary to other autoimmune diseases (SLE)
• Females (40-50)
• family history
• HLAB8/DR3

Question 3

age

Answer 3

40-50

Question 4

Symptoms of Sjogren syndrome? (4)

Answer 4

1) Dry eyes (keratoconjuctivitis sicca)
2) Dry mouth (xerostoma)
3) Dry vagina
4.) Enlarged parotid gland

Question 4

Treatment of Sjogren’s? (2)

Answer 4

Artificial tears, saliva + lubricant for sexual activity

*Sometimes hydroxychloroquine given for fatigue, myalgia and rashes (up to dr)

Question 5

Investigations to diagnose Sjogren syndrome? (2)

Answer 5

Serology = anti-RO + anti LA Ab’s (ANA often +ve)

Schrimer test = induce tears + place filter paper under eyes-tears travel <10mm (should be 20mm+)

Question 6

Complication/association of Sjogrens?

Answer 6

Directly confers an increase risk of lymphomas

Question 7

antibodies

Answer 7

anti-RO + anti LA Ab’s
ANA often +