psoaritic arthiritis Flashcards
1
Q
What % of people who have psoriasis develop psoriatic arthritis?
A
10-40% within 10 years
2
Q
Treatment of psoriatic arthritis? (5)
A
Symptoms = NSAIDS
DMARD = methotrexate most commonly if it occurs outside the spine
- if that fails = anti TNF (infliximab, etanercept)
- if that fails IL 12+23 inhibitors (ustekinumab)
- IL 17 blockers (secukinumab)
2
Q
Severe symptom/complication of psoriatic arthritis?
A
Arthritis mutilans (5%) = pencil in cup deformity:
- osteolysis of bone = progressive shortening
- fingers telescope in on themselves
3
Q
Moderate symptoms of psoriatic arthritis? (5)
A
- Inflamed distal interphalangeal joints
- Nail pitting - notches in nails
- Dactylitis
- Enthesitis
- Psoriatic rash on skin
3
Q
Areas of the body affected with psoriatic arthritis? (3)
A
- different patterns occur
- Spine
- asymmetrical big joints
- symmetrical polyarthiritis
- usually DIP affected
