Sjogrens Flashcards
1
Q
Sjogrens features
A
Lymphocytic infiltration of exocrine glands,sicca symptoms,circulating auto abs
2
Q
Renal manifestations in Sjogrens
A
Type 1RTA
3
Q
Neurologic involvement in Sjogrens
A
Pseudoathetosis
4
Q
Most common lymphoma in Sjogrens
A
6-19x risk for NHL
MALT lymphoma most common
5
Q
Autoantibody in Sjogrens
A
SSA(Anti-Ro) in 2/3,often with SSB RF in 50% ds DNA typically absent Polyclonal hypergammaglobulinemia Cryoglobulinemia in 15%
6
Q
Antibody in Sjogrens with risk of causing neonatal heart block
A
SSA/Ro crosses placenta and can cause conduction defects
