SIRS, DIC, ARDS & VENTILATORS Flashcards
SIRS occurs due to a widespread, _______ release of ________ in response to an
acute physiologic insult or injury.
- SYSTEMIC (rather than localized)
* chemical mediators of inflammation
Almost all ____ patients have SIRS, however, not all SIRS patients are ______.
- Septic
* Septic
For SIRS, what do you wan to treat? What other two things should be included?
- Underlying cause (example: infection)
* Include DVT and Stress ulcer prophylaxis
What four Items are look at to diagnose SIRS? How many of the 4 are needed?
- TEMP
- RR
- HR
- WBC
At least two of the four
The temperature criteria for sirs is Less than ____ and greater than _____.
The RR Criteria is _____ ?
The HR criteria is ____?
WBC criteria is less than _____, greater than ____ or More than ______ are ______.
- Less Than 36 degrees C (96.8) and Greater than 38.3 degrees C (101).
- Tachypnea (>/= 20/min)
- Tachycardia (>/=90/Min)
- WBC =4,000 or >/= 12,000 OR >10% wbc are immature
QUICK SEPSIS ORGAN FAILURE
ASSESSMENT - (Qsofa) what are the criteria for this assessment.
ALF
- Altered mental status - (GCS <15)
- Low BP (SBP=<100)
- Fast RR (RR>=22)
DIC- A syndrome where _____ and _____occur as a result of an abnormal overstimulation of the normal coagulation process due to what 3 things?
- Thrombosis (Clotting) and Hemorrhage
* Severe injury, illness, sepsis,
Major initiating factors of DIC are the release of _________ secondary to extensive injury to tissues, leading to more _____being produced. This causes extensive_____. Because all the _____ are being used, this can result in ______.
- tissue factor (thromboplastin)
- Fibrin
- Clotting throughout capillaries
- Clotting factors (Platelets)
- Hemorrhage
The extensive formation of clots can lead to what three things?
*Ischemia, necrosis, organ damage.
First sign of DIC?
- Bleeding/oozing blood
* Petechiae and ecchymoses can be seen as well.
Labs for diagnosing DIC:
- Platlets
- PT ?
- PTT ?
- Plasma fibrinogen?
- D-dimer levels and FDP?
- Thrombocytopenia (< 100,000)
- prolonged (due to consumption of coag factors)
- prolonged (due to consumption of coag factors)
- decreased(due to consumption of coag factors)
- Elevated (Fibrin being formed)
Treatment for DIC? 3 things.
- Underlying causes
- Replacement blood products
- Anticoagulants
A clinical syndrome characterized by the development of progressive physiologic dysfunction in 2 or more organs, or organ systems, that is induced by a variety of acute physiologic insults. What is this? where does this usually begin? What is key?
- MODS - (progressive stage of shock)
- Lungs, others follow
- Prevention
SIRS + known or suspected infection
Sepsis
A hallmark sign and symptom found in ARDS is refractory _____. No improvement even when on _____.
- refractory hypoxemia
* 100% oxygen