SIRS and Shock Flashcards
Adults SIRS Criteria
temp more than 38/100.4 or less than 36/96.8
heart rate greater than 90
rr greater than 20 or paco2 less than 32
wbc more than 12k, less than 4k or more than 10% bands
Peds SIRS Criteria
temp more than 38.5 (101.3) or less than 36 (96.8)
tachycardia or bradycardia if less than 1 year
tachypnea or mechanical ventilation
abnormal lecukocyte count or more than 10% bands
Sepsis
SIRS + source of infection
Severe Sepsis
sepsis + organ dysfunction (hypotension, hypoperfusion)
Septic Shocks
severe sepsis despite adequate fluid resuscitation
Multiple Organ dysfunction syndrome
evidence of 2 or more organs failing
tachycardia/pnea for peds
mean rate more than 2 standard deviations above normal
bradycardia - peds
mean heart rate less than 10th percentile for age
severe sepsis in peds
associated with cardiovascular dysfxn, ARDS, or dysfxn in two or move organ systems
goal CVP
12
a1 and a2 receptors
blood vessels
vasoconstriction
b1 receptors
myocardium
inotrope
chronotrope
inotrope
?
chronotrope
?
b2 receptors
blood vessels
vasodilation
d1 receptors
renal
vasodilation
norephineprhine receptors
a1
ba
norephinephrine AE
arrhythmias
pnehylephine receptors
alpha 1
epinephrine receptors
potent b1 (1st) alpha 1 (2nd) some b2
dopamine receptors
low dose d1
medium dose b1
high dose a1
dobutamine
b1 and b2
dobutamine used for
cardiogenic shock and htn (decompensated HF)
septic shock, give
NE
PE if arrhythmia develops
cardiogenic shock, give
dopamine if hypotension
dobutamine if hypertension
compliance
delta v / delta p
preload =
gas tank
contractility =
engine
afterload =
exhaust system
tension or stress developed in wall of LV during ejection
in other words the end load against which the heart contracts to eject blood
hypovolemic shock primary problem
decreased preload
hypovolemic - contractility
initially increases, increase SV
hypovolemic - afterload
increase, trying to vasoconstrict
cardiogenic shock - primary problem
contractility decreased
cardiogenic preload
increased or normal, heart isn’t pumping
cardiogenic afterload
increased, because want to keep bp up
treatment of cardiogenic shock
afterload reduction (nitrates)
neurogenic - primary problem
decreased afterload
what causes neurogenic shock
sympathetic damage, c6/7 or above
neurogenic - preload
up or down
vasodilation causes preload to go down
pooling of blood causes preload to go up
neurogenic contractility
increased
sepsis - primary problem
decreased preload, contractility and afterload
swann meausres
pulmonary artery pressure
best estimate of what’s getting into LA and LV
normal SVO2
76%, optimal above 70%
svo2 too low
not getting enough oxygen
svo2 too high
tissues not absorbing oxygen, person is dead