Signalling 1 - Intro Flashcards
state 5 different types of signalling molecules
- protein - insulin, fibroblast growth factor
- small hydrophobic molecules - animal steroid hormones
- small hydrophilic molecules - plant auxins
- gas - ethylene, nitric oxide
- electrical - nerve impulses
What are the 3 different types of signalling based on their ranges?
- endocrine - long range
- paracrine - intermediate range
- contact-dependent - juxtacrine
what is endocrine signalling?
uses the bloodstream
what is paracrine signalling?
diffusion along intermediate distances
What is juxtacrine signalling
- contact dependent
- the signal never leaves the cell
give 3 examples of endocrine signals
- male and female hormones in sexual dimorphism
- flowering plants triggered by day length
- the nervous system
what are competent cells?
cells able to respond to a signal
What are incompetent cells?
cells unresponsive to a signal
how is endocrine signalling used in plant flowering?
- allows plants to time their signalling in a accordance to day length
- allows plants of the same species to flower at the same time
- sensor for light (CO protein) found in the leaf
- CO is a TF
- CO accumulates when days are long
- high CO, promotes synthesis of FT protein
- FT high when days are long
- FT move through sap from leaf to shoot
- flower forms at shoot
Hoe does the nervous system use paracrine and juxtacrine signalling?
- axon navigation is determined by where the growth cone grows
- growth cone has receptors for guidance molecules
- paracrine - growth cone reacts as it gets close to this signal
- juxtracrine - growth cone reacts when it comes into contact will the cell expressing these signals
What are cells secreting axon guidance signals called?
guidepost cells
Explain electrical transmission between nerve cells
- signal moces alonf pre-synaptic cell
- cells contact each other at synapse - axon of one touches body of other
- electrical signal moves along post synaptic cell
explain signalling at the synapse
- nerve impulse causes pre-synaptic cell to release a neurotransmitter
- neural transmitter travels a short distance across the synapse and binds to receptors on post-synaptic cell
- triggers nerve impulse in post synaptic cell
- nerve cells also synapse with muscle cells