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Simmons Pharm 2 Exam 3 > Side Effects > Flashcards

Side Effects Flashcards

1
Q

May bleach clothing or hair

A

Benzoyl Peroxide

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2
Q

Turmorigenic

A

Tretinoin (Retin-A)

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3
Q

Regular retinoid that can’t be used during pregnancy.

A

Tazarotene (Tazorac)

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4
Q

Dryness, itching of mucous membranes and skin.

A

Isotretinoin (Accutane)

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5
Q

Premature close of epiphyses.

A

Isotretinoin (Accutane)

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6
Q

HPA axis suppression

A

Topical corticosteroids

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7
Q

Skin atrophy

A

Topical corticosteroids

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8
Q

Rosacea

A

Topical corticosteroids

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9
Q

Hypopigmentation

A

Topical corticosteroids

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10
Q

Hypertrichosis

A

Topical corticosteroids

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11
Q

Viral infections

A

Calcineurin inhibitors

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12
Q

HSV

A

Calcineurin inhibitors

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13
Q

Molluscum

A

Calcineurin inhibitors

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14
Q

Varicella

A

Calcineurin inhibitors

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15
Q

Asthma

A

Calcineurin inhibitors

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16
Q

Hepatitis, increased liver enzymes

A

Azole antifungals

PTU

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17
Q

Inhibits CYP450 more than newer azoles.

A

Ketoconazole (Nizoral)

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18
Q

Increased hair loss or change in hair texture.

A

Ketoconazole (Nizoral) topical

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19
Q

Gynecomastia

A

Ketoconazole (Nizoral) systemic

Antipsychotics

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20
Q

Hepatic dysfunction

A

Terbinafine (Lamisil) systemic
Griseofulvin
Ganciclovir
Strattera (Atomoxetine)

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21
Q

Odor, discoloration, hair loss

A

Selenium sulfide (shampoo)

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22
Q

Nephrotoxicity

A

Acyclovir family

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23
Q

IV drug associated with nephrotoxicity and neurological effects

A

Acyclovir

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24
Q

Confusion, hallucinations, seizures

A

Valacyclovir

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25
Q

Thrombocytopenic purpura

A

Valacyclovir

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26
Q

Hemolytic uremic syndrome

A

Valacyclovir

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27
Q

Myelosuppression

A

Ganciclovir

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28
Q

Peripheral neuropathy

A

Ganciclovir

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29
Q

Mutagenic and carcinogenic, embryogenic in animals

A

Ganciclovir

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30
Q

Flu-like symptoms

A

Imiquimod

Withdrawal of SSRIs

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31
Q

Severe conjunctivitis if contact with eye

A

Podophyllum resin

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32
Q

Toxicity includes: nausea, vomiting, alterations in sensorium, muscle weakness, neuropathy, coma, death.

A

Podophyllum resin

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33
Q

Neuroleptic malignant syndrome

A

Antipsychotics

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34
Q

EPS

A

Typical antipsychotics more so than atypicals

35
Q

Allergic dermatitis

A

Antipsychotics

36
Q

Amenorrhea

A

Antipsychotics

37
Q

Leukopenia, agranulocytosis, leukocytosis

A

Atypical (2nd generation) antipsychotics

38
Q

Arrhythmias

A

Antipsychotics

39
Q

EPS in newborns

A

All antipsychotics

40
Q

Most weight gain/metabolic effects of the antipsychotics

A

Olanzapine

41
Q

Increases mortality in elders

A

Atypical (2nd generation) antipsychotics

42
Q

Highest risk for agranulocytosis

A

Clozapine

43
Q

Nausea and loose stools

A

SSRIs

44
Q

Sexual dysfunction

A

SSRIs

45
Q

Weight gain

A

SSRIs

Antipsychotics

46
Q

Serotonin Syndrome

A

SSRIs

47
Q

FLUSH

A

SSRI withdrawal

48
Q

Depression, suicidal ideation in those 24 and under.

A

SSRIs

49
Q

Pulmonary HTN in newborn

A

SSRIs

50
Q

Prolonged QT

A

SSRIs

51
Q

Central nervous system depression

A

Benzodiazepines

52
Q

Excessive sedation

A

Benzodiazepines

53
Q

Physiologic dependence

A

Benzodiazepines

54
Q

Shorter half-life than all benzos

A

Flumazenil (Romazicon)

55
Q

Seizures and cardiac arrhythmias for patients who also ingest tricyclics

A

Benzodiazepines

56
Q

Anorexia

A

Stimulants

57
Q

Delayed sleep onset

A

Stimulants

58
Q

Worsening of tics

A

Stimulants

59
Q

Increased blood pressure

A

Stimulants

60
Q

Growth deceleration

A

Stimulants

61
Q

Blood dyscrasias

A

Stimulants

62
Q

Rebound effect (with short-acting)

A

Stimulants

63
Q

Priapism

A

Stimulants

64
Q

Suicidal ideation in all age ranges

A

Strattera (Atomoxetine)

65
Q

GI discomfort, vomiting, fatigue, anorexia

A

Strattera (Atomoxetine)

66
Q

Mood swings

A

Strattera (Atomoxetine)

67
Q

Increase in blood pressure and heart rate

A

Strattera (Atomoxetine)

68
Q

Mania

A

Strattera (Atomoxetine)

69
Q

Agitation

A

Strattera (Atomoxetine)

70
Q

Rebound HTN if suddenly discontinued

A

Clonidine

71
Q

Hypotension, anorexia, arrhythmias, depression

A

Clonidine

72
Q

Weight loss

A

Modafanil

73
Q

Stevens-Johnson Syndrome

A

Modafanil

74
Q

Seizures during activation

A

Bupropion (Wellbutrin) (less likely with SR and XL forms)

75
Q

Esophageal injury

A

Bisphosphonates

76
Q

Jaw osteonecrosis

A

Bisphosphonates

77
Q

Atypical femur fracture

A

Bisphosphonates

78
Q

Diffuse muskuloskeletal pain

A

Bisphosphonates

79
Q

Thromboembolism

A

Raloxifine (Evista)

80
Q

Muscle weakness

A

Deficiency of Vitamin D

81
Q

Chronic pain

A

Deficiency of Vitamin D

82
Q

Hypercalcemia

A

Vitamin D

83
Q

Polydipsia, polyuria, confusion, fatigue

A

Vitamin D toxicity

Simmons Pharm 2 Exam 3 (5 decks)

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