Misc Flashcards
When do you recheck Vitamin D?
Typically after 3 months of therapy
What is toxicity for Vitamin D?
> 150 ng/dL
Why does so much bone loss occur around menopause?
Estrogen is protective against bone loss.
What can a high calcium level indicate?
Problem with parathyroid. Low Vitamin D, high Calcium. A parathyroid problem will increase bone breakdown.
What is a risk factor for younger women and osteoporosis?
Surgical menopause
Does HYPO- or HYPERthyroidism count as a risk factor for osteoporosis?
HYPOthyroidism
Do bisphosphonates act on osteoblastic or osteoclastic activity?
Osteoclastic
When do you take bisphosphonates?
On an empty stomach (30 minutes before).
What decreases absorption of bisphosphonates?
OJ and coffee
What is the T5 of bisphosphonates?
Exceeds 10 years
Which osteoporosis med can be taken without regard to meals?
Raloxifene (Evista)
What is the onset of Raloxifene (Evista)?
8 weeks
Which thyroid med has risk of liver damage?
PTU
How do you take Levothyroxine?
On an empty stomach
Strattera has a lot of drug interactions, but particularly with what kind of meds?
Antidepressants
Which PO med is poorly absorbed from the GI tract and so only effective for infections of GI tract?
Amphotericin B
Why aren’t imidazole antifungals given orally?
Not absorbed from GI tract.
What clinical pearl can help with diagnosis of fungal vs dermatitis?
If you treat fungus with a steroid cream, it will get worse.
If you treat dermatitis with an antifungal, it will most likely not improve.