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neurobiology > side effect neurotransmitters > Flashcards

side effect neurotransmitters Flashcards

1
Q

constipation, blurred vision and dry mouth in TCAs

A

M1, M3

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2
Q

hypersalivation in clozapine

A

M4

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3
Q

hypertension in venlafaxine

A

noradrenergic receptiors

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4
Q

TD in Antipsychotics

A

dopamine supersensitivity

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5
Q

parkinsonism and dystonia in antipsychotics

A

dopamine receptor blockade in substantia nigra

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6
Q

hypotension in olanzapine and quetiapine

A

alpha adrenergic receptor blocking- post synaptic alpha 1

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7
Q

sexual dysfunction in SSRIs

A

5HT2C

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8
Q

Anxiety in SSRIs

A

5HT1A

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9
Q

nausea in SSRIs

A

5HT3

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10
Q

hyperprolactinaemia in antipsychotics

A

D2 in tuberoinfundibular system

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11
Q

weight gain and sedation in mirtazapine

A

5HT2C, H1

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12
Q

weight gain in antipsychotics

A

H1, 5HT2C

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13
Q

better EPSEs in atypical antipsychotics

A

5HT2 antagonism and increased dopamine in SN with D2 antagonism in mesolimbic system

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14
Q

increased anxiety with salbutamol

A

beta adrenergic

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15
Q

better anxiety with propanolol

A

beta adrenergic

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16
Q

memantine

A

NMDA receptor antagonist

17
Q

tolerance to halluconogens

A

5-HT 2A receptor desenstitisation

18
Q

Benzo withdrawal

A

decreased Brain GABA

19
Q

trazadone

A

5HT-2 receptor binding, blocks serotonninreuptake

20
Q

trazodone sedation

A

H1 antagonism, alpha blocking

21
Q

irregular periods with antipsychotics

A

D2 antagonism

22
Q

NMS

A

D2 blockade

23
Q

priapism

A

5HT2A/5HT2C, alpha 1 antagonism

24
Q

weight gain and sedation

A

H1 antagonism

25
Q

obsessive compulsive symptoms in antipsychotic use

A

5HT1D

26
Q

sedative action in trazodone

A

H1 antagonism

27
Q

smooth muscle

A

M3 blockade

28
Q

CNS

A

M4

29
Q

Heart

A

M2

30
Q

priapism

A

Alpha 1

31
Q

initial energy boost with SSRIs

A

5HT2C antagonism

32
Q

morning drowsiness on atypical antipsychotics

A

H1 antagonism

33
Q

constipation on TCA

A

M1

34
Q

hypnotic effect of zopiclone

A

GABA agonism

neurobiology (13 decks)

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