Sickle Cell Crises

Question 1

Painful

Answer 1

Thrombotic

Question 2

Precipitants of thrombotic (3)

Answer 2

Infection
Dehydration
Deoxygenation

Question 3

Increased reticulocytes

Answer 3

Sequestration

Question 4

Sequestration crisis cause

Answer 4

Sickling within organs e.g. spleen or lungs —> pooling of blood —> worsening of anaemia

Question 5

Acute chest syndrome cause

Answer 5

Vaso occlusion within pulmonary microvasculature —> infarction in lung parenchyma

Question 6

Acute chest syndrome symptoms (4)

Answer 6

Dyspnoea
Chest pain
Pulmonary infiltrates on CXR
Low pO2

Question 7

Acute chest syndrome treatment (4)

Answer 7

Pain relief
Oxygen
Antibiotics
Transfusion

Question 8

Reduced reticulocyte count

Answer 8

Aplastic

Question 9

Cause of aplastic

Answer 9

Infection w/ parovirus

Question 10

Sudden fall in Hb

Answer 10

Aplastic