Sickle Cell Flashcards

1
Q

HbF

HbA

HbA2

A

HbF high

HbA absent

HbA2 normal

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2
Q

Symptoms

A

Heart problems

Bone pain

Stroke

Leg ulcers

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3
Q

Treatment

A

Pneumovax 2

Lifelong penicillin

Avoid triggers

Folic Acid

HSCT

Iron chelation / splenectomy

Gene therapy

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4
Q

Pathology of sickle

A

Mutation in B globin

RBC gets sequestered and destroyed

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5
Q

MCV

MCH

MCHC

A

Normochromic

Normocytic

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