Sickle Cell Flashcards
1
Q
HbF
HbA
HbA2
A
HbF high
HbA absent
HbA2 normal
2
Q
Symptoms
A
Heart problems
Bone pain
Stroke
Leg ulcers
3
Q
Treatment
A
Pneumovax 2
Lifelong penicillin
Avoid triggers
Folic Acid
HSCT
Iron chelation / splenectomy
Gene therapy
4
Q
Pathology of sickle
A
Mutation in B globin
RBC gets sequestered and destroyed
5
Q
MCV
MCH
MCHC
A
Normochromic
Normocytic