HbH Flashcards
1
Q
Pathology
A
3 gene deletion
B globin excess
Hb precipitated removed by macro in spleen. Extravascular haemolysis
Intravascular haemolysis from Hb precipitates
2
Q
MCV / MCHC / MHC
A
Microcytic Hypochromic
3
Q
Treatment
A
AB for E.coli infections (gram negative)
Regular Folic acid
Splenectomy
Basically do nothing
4
Q
HbA / HbF / HbA2
A
HbA - reduced
HbF - Normal
HbA2 - Normal
