SI Flashcards

1
Q

Epidemiology (small and large bowel)

A

60+
4th most common
decrease by 11% by 2035

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Aetiology

A

smoking
diet (28% too little fibre)
Crohn disease
Lynch disease
radiation
polyps: benign mass in the bowel which becomes cancerous
coeliac disease
genetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

give info on bowel screening

A

58-74 years
saves 9/10 people
every 2 years
faecal sample delivered in the post
improves the outcome, gives a better prognosis increasing the survival rate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the type of pathology

A

Adenocarcinoma (40%)
Lymphomas
NETs
Sarcoma (soft tissue in the ileum)
Leiosarcomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What staging is used?

A

TNM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where does met spread come from?

A

Pancreas and ovaries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Where does local spread go to?

A
  • other regions of the SB
  • if in the duodenum, then it can spread to the pancreas
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Where does the lymphatic spread travel to?

A

mesenteric, colorectal patients tend to have mets in the liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Where does haematological spread go to?

A

lung, liver, bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What can’t be formed during a diagnosis?

A

a biopsy, due to the high risk of perforation, therefore a laparoscopy is performed after a CT/MRI and barium swallow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the presentations?

A

weightloss
malnutrition
fatigue
descended stomach (stomach)
blood in stools, depends on the tumour location could be black or red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is completed during diagnosis

A

CT/MRI
laparoscopy: opens the whole abdomen, there are recovery issues
barium swallow
blood test
capsule endoscopy: capsule contains a camera, which follows the digestive pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what treatment options are there

A

surgery, chemotherapy, radiotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

describe surgery

A

dependent on the location
part of the bowel can be removed with the remaining being re-connected
pancreatico-duodectomy
ileostomy: stoma bag
may be followed up by chemo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

describe RT

A

very uncommon, due to constant motion, there is a high risk of ulceration
maybe to the mesenteric nodal group
palliation: ant and post field with 20Gy in 5 or 30Gy in 10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

describe chemo

A
  • 5-FU
  • cape
  • oxaliplatin
  • Iirinotecan (can be used in combo)
17
Q

what drug is not used for chemo for small, large and rectum

A

cis-platin

18
Q

what type of cancer may receive some RT

A

lymphomas as low dose can be used + chemo (vincristine/ doxorubicin)

19
Q

what is the prognosis

A

70/80%