LI Flashcards
presentation
dependent on the tumour location
obstruction is more common in the descending colon due to more curves especially near the colon
pathology
adenocarcinoma
what are the types of spread
local, lymphatic, blood
where does local spread go to
liver, within itself, small bowel
where does lymphatics travel to
mesenteric
how is the tumour diagnosed
CT/MRI
endoscopy
LFT
biopsy
what is the system used for staging
duke system, however TNM is now more common
what treatment is for early stages
surgery: bowel reconnection and chemotherapy
what treatment is for late stages
surgery, chemo, RT (however causes secondary malignancies), immunotherapy, targeted cancer drugs
what are the targeted cancer drugs
Cetuximab, Panitumab, Bevacizumab
monoclonal antibody trials
what is FAP
Familial Adeno Polypsis
what can be done about FAP
the bowel can be removed to prevent cancer, due to the there being a large number of bowel polyps, these could become cancerous if not treated
Lynch syndrome
doesn’t have as many bowel polys, but has a higher risk of other cancer types
