Shortness of Breath Flashcards
What are the three categories of why someone might be breatheless?
Not enough oxygen reaching the lungs
Not enough reaching the blood
Not enough reaching the rest of the body
What are the cardiac causes of breathlessness?
Heart Failure
Cardiomyopathy
Constrictive Pericarditis
Myocarditis
Define heart failure
The failure of the heart to maintain CO to meet body’s demands
How can HF be classified?
Acute or Chronic
Left or Right or Both
High or Low output state
What is HF where both sides of the heart are effect known as?
Congestive HF
What is the natural history of Congestive HF?
LH to start
Pressure backs up into the pulmonary system
Backs up into RH
What is low output state HF?
Heart fails to pump un response to normal exertion
Low CO
What is high output state HF?
CO is normal but higher metabolic needs
e.g. pregnancy, anaemia and hyperthyroidism
What are the causes of LHF?
Valvular
Muscular
Systme
What are the valvular causes of LHF?
Aortic stenosis
Aortic regurg
Mitral regurg
What are the muscular causes of LHF?
IHD
Cardiomypopathy
Myocarditis
Arrythmias
What are the systemic causes of LHF?
HTN
Amyloidosis
Drugs e.g. cocaine, chemo
What are the causes of RHF?
Lungs
Valvular
What are the lung related causes of RHF?
Pulmonary HTN
PE
Chronic lung ddisease
What are the valvular causes of RHF?
Tricuspid regurg
Pulmonary valve disease
High output heart failure causes?
NAP MEALS
Which vein does the LHS of the heart receive blood from?
Pulmonary veins
What causes symptoms in LHF?
Fluid accumulates in lungs –> respiratory systen
What causes symptoms in RHF?
Fluid accumulates in the peripheries –> swelling signs
What are the symptoms of LHF?
Dyspnoea
Nocturnal cough (pink, frothy sputum)
Fatigue
What types of dyspnoea can be present in LHF?
Paroxysmal nocutrnal
Exertional
Orthopnoea
What cardiac signs are present in HF?
High HR High RR Irregulary irregular pulse Pulsus alternans Dispaced apex beath S3 Gallop S4 in severe HF Murmur (AS, MR, AR)
Why do we get signs in LHF?
Consequence of HF
Because of the underlying cause of the HF
What are some signs of RHF?
Face swelling
Raised JVP
Weight gain
Ascites
What investigations should be done for HF?
ECg
FBC, U&Es, LFTs, TFTs, BNP
CXR, TTE
Why do a CXR for HF?
Rule out MI
What is a TTE?
Trans-thoracic echocardiography
Gold standard for HF
What is BNP? When is it raised?
Released when heart muscle stretches
What is the issue with BNP?
Sensitive but not specific
If high need to do TTE to confirm
What does TTE allow us to do?
Visualise the structure and function of the heart
Calculate the EF
What are the CXR signs for HF?
Alveolar oedema B-lines Cardiomegaly Dilated upper lobe vessels Diverted upper lobe Effusion
What is the criteria for HF diagnosis clinically?
Framingham criteria
What are the major framingham criteria?
Paroxysmal nocturnal dyspnea
Weight loss of 4.5 kg in 5 days in response to treatment
Neck vein distention
Rales
Acute pulmonary edema
Hepatojugular reflux
S 3 gallop
Central venous pressure greater than 16 cm water
Circulation time of 25 seconds or longer
Radiographic cardiomegaly
Pulmonary edema, visceral congestion, or cardiomegaly at autopsy
What are the minor framingham criteria?
Ankle edema, night cough, dyspnea on exertion, hepatomegaly, tachycardia and weight loss
What is the management for Chronic HF?
Treat underlying cause
Treat the exacerbating factors
Lifestyle modification
Drugs
What are the drugs for HF?
ABD Villiers
ACE inhibitors
Beta Blockers
Diuretics
In which HF patients should ACE inhibitors be given?
Anyone with LV dysfunction
Why are beta blockers used?
To reduce O2 demand
What can be used in place of ACEi if not tolerated?
ARB
Sometimes get cough with ACEi
When are diuretics used?
Evidence of fluid retention
What are some ACEi?
-pril
What are some Beta blockers?
-olol
What are some diuretics?
Furosemide
Define cardiomyopathy
A group of diseases in which the myocardium becomes structurally and functionally abnormal
- in the absence of CAD, valvular disease and congenital heart disease
What are the types of cardiomyopathy?
Dilated
Hypertrophic
Restrictive
What are the types of cardiomyopathy?
Dilated
Hypertrophic
Restrictive (less compliant muscle)
How might cardiomyopathy present?
HF symptoms
SOB on exertion
Fainting
Fatigue
Ask about FH
Esp. sudden death
Signs of cardiomyopathy on examination?
Respiratory crackles
Murmurs S3, S4
Describe the pathophysiology of dilated cardiomyopathy?
Ventricles enlarge and become dilated
Walls thin and weaken, cannot contract well
Law of LaPlace
What are the RFs for dilated cardiomyopathy?
Alcohol
Post-viral
Haemochromatosis
Genetic
What are the signs of dilated cardiomyopathy?
Displaced apex beat
TR/MR murmur
SM
What will you see on investigation in dilated cardiomyopathy?
Globular heart CXR
What is the pathophysiology for HOCM
H for hench
Muscle thickens inward
Increased stiffness
Thickened muscle disrupts electrical conduction
What are the symptoms of HOCM?
Usually asympto Sudden cardiac death Angina Dyspnoea on exertion Palpitations Syncope
What are the signs of HOCM?
Ejection systolic murmur
Jerky carotid pulse
Double apex beat NOT DISPLACED (muscles grows inwards)
S4
What is the pathophysiology of restrictive cardiomyopathy?
R for rigid
Ventricles become abnormally rigid and lose flexibility
Impaired ventricular filling
Reduced preload
Reduced blood flow and backing up of blood
What are some causes of restrictive cardiomyopathy?
Sarcoidosis
Amyloidosis
Famililal
Idiopathic
What does HOCM stand for?
Hypertrophic cardiomyopathy
What are the causes of constrictive endocarditis?
Idiopathic
Infectious (TB, ba
Acute pericarditis
Cardiac surgery and radations
What are the signs/symptoms of constrictive pericarditis?
Similar to restrictive cardiomyopathy
RHF presentation
Kussmaul’s
What are the investigations for constrictive pericarditis?
CXR - pericardial calcification
Echo - increased pericardial thickness
What are the causes of constrictive endocarditis?
Idiopathic
Infectious (TB, bacterial, viral)
Acute pericarditis
Cardiac surgery and radations
What are the causes of myocarditis?
Infectious Drugs Metals Radiation Coxsackie B virus
What are the signs and symptoms of myocarditis?
Flu-like prdome
Chest pain
SOB
Palp
Define myocarditis
Inflammation of the myocardium
What are the signs and symptoms of myocarditis?
Flu-like prodome
Chest pain
SOB
Palpitations