Sarcoidosis Flashcards
1
Q
Define sarcoidosis
A
Sarcoidosis is a chronic granulomatous disorder of unknown aetiology, commonly affecting the lungs, skin, and eyes
Bimodal 3rd anf 5th decades
2
Q
What is the characteristic feature of sarcoidosis?
A
Accumulation of lymphocytes and macrophages
Non-caseating granulomas in lungs etc.
3
Q
What are key presenting features of sarcoidosis?
A
Cough Dyspnoea Chronic fatigue Arthralgia Wheeze Lymphadenopathy Photophobia Red painful eye Blurred vision
4
Q
How is sarcoidosis diagnosed?
A
Clinically Bloods - hypercalcaemia, raised ESR CXR Spirometry - restrictive disease Tissue biopsy
5
Q
What might be seen on CXR in sarcoidosis?
A
stage 0 = normal
stage 1 = bilateral hilar lymphadenopathy (BHL)
stage 2 = BHL + interstitial infiltrates
stage 3 = diffuse interstitial infiltrates only
stage 4 = diffuse fibrosis
6
Q
What is the management for acute resp failure sarcoidosis?
A
IV/Oral corticosteroid
Ventilatory support and O2
