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Immunology > Short List Drugs > Flashcards

Short List Drugs Flashcards

1
Q

ipilimumab

A

anti CTLA-4 antibody

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2
Q

abatacept

A

CTLA-4 (cd152) Ig

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3
Q

pidilizumab

A

anti PD1 antibody

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4
Q

samalizumab

A

anti 200 antibody

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5
Q

another name for anti-BLys and what it treats

A

Benylysta – BR3 receptor is its target

treats systematic lupus

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6
Q

rituximab and what it treats

A

anti CD20 antibody (think IgG)

rheumoid arthritis

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7
Q

binds TNF

A

remicade, humicade, humira, simponi

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8
Q

anti VLA4 antibody

A

natalizumab

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9
Q

what is dormant in the body until natalizumab activates it

A

polyomavirus

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10
Q

zanapax/Daclizumab

A

anti IL2R aka anti CD25

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11
Q

another anti-IL2R

A

basiliximab

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12
Q

what do the anti CD25 affect and not affect

A

they affect T cells but not Tregs so decreased T cells and increased Tregs leads to suppression of the immune system

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13
Q

anti p40

A

Ustekinumab and Briakinumab

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14
Q

target of ustekinumab and briakinumab

A

IL-12 (p40 and p35)

IL-23 (p40 and p19)

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15
Q

anti C5 antibody

A

eculizumab

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16
Q

what does eculizumab protect

A

PNH until it is opsonized by C3

17
Q

binds IgE

A

xolair/omalizumab

18
Q

problem with xolair

A

you have no release of allergen mediators so susceptible to asthma and allergens

Immunology (6 decks)

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