Shock Syndromes Related to Sepsis

Question 1

This is simply the presence of bacteria in the blood, can be harmless bacteria, such as those found in the oral flora.

Answer 1

Bacteremia

Question 2

This is an inflammatory state affecting the entire body caused by the immune system.

Answer 2

Systemic Inflammatory Response Syndrome (SIRS)

Question 3

What are the 3 causes of SIRS?

“why… so…. sirs??”

Answer 3

sepsis, trauma, burns

Question 4

Generally, this is the whole body inflammatory response to an infection.

Answer 4

Sepsis

Question 5

This is the end stage of sepsis that included multiple organ failure, ↓ BP, high fever, vasodilation, sludging of blood, and DIC.

Answer 5

Septic shock.

Question 6

These are components of G- bacteria that and endotoxins that stimulate a range of host responses and activate nearly every immune mechanism.

Answer 6

LPS

Question 7

LPS activation of the complement system can cause an overload of the vasculature with PMN’s, leading to what condition?

Answer 7

DIC

Question 8

This is the cytokine that is the most important activator of inflammatory cells.

Answer 8

TNF-a

Question 9

What is the toxin from S. aureus to cause septic shock, and is comoon in young women?

Answer 9

TSST1

Question 10

This is the toxin from mycobacteria that cause toxic shock.

Answer 10

Lipoarabinomannan