Cardiac Transplantation

Question 1

Scenario: you are James Woods, a well known cardiothoracic surgeon, and Denzel Washington is pointing a gun at your head telling you to that “I will not bury my son…. my son… will bury me.” Will you cut out the heart from Denzel’s chest and implant it in his son to save his son’s life?

Answer 1

No because my ex-gf is horrible.

Question 2

What are the 3 criteria to improve the outcome for cardiac transplantation?

Answer 2

1. Effective immunosuppressive therapy (cyclosporin A, glucocorticoids, etc)
2. Careful selection of candidates
3. Early histopathologic Dx of acute allograft rejection.

Question 3

What is the only major complication that requires surveillance in transplants?

Answer 3

Allograft rejection

Question 4

How do u Dx therejection before too much dmg occurs?

Answer 4

Scheduled endomyocardial biopsy

Question 5

What change can the coronary arteries undergo to limit the long term success of transplant?

Answer 5

Diffuse stenosing from intimal proliferation

Question 6

What is the 5 year survival rates of cardiac transplant?

Answer 6

74%

Question 7

What is the 10 year survival rates of cardiac transplant?

Answer 7

55%